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Gramelspacher et al., 2020 - Google Patents

Biochemical characterization of RNA-guided ribonuclease activities for CRISPR-Cas9 systems

Gramelspacher et al., 2020

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Document ID
17486299426609440456
Author
Gramelspacher M
Hou Z
Zhang Y
Publication year
Publication venue
Methods

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Snippet

The majority of bacteria and archaea rely on CRISPR-Cas systems for RNA-guided, adaptive immunity against mobile genetic elements. The Cas9 family of type II CRISPR- associated DNA endonucleases generates programmable double strand breaks in the …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

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