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Mules et al., 1998 - Google Patents

In vivo Ty1 reverse transcription can generate replication intermediates with untidy ends

Mules et al., 1998

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Document ID
1736384375570817508
Author
Mules E
Uzun O
Gabriel A
Publication year
Publication venue
Journal of virology

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Ty1 retrotransposition, like retroviral replication, is a complex series of events requiring reverse transcription of an RNA intermediate, RNA-primed minus-and plus-strand DNA synthesis, multiple strand transfers, and precise cleavages of the template and primers by …
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
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    • C12N2740/00—Reverse Transcribing RNA Viruses
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