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Han et al., 2019 - Google Patents

Multivalent aptamer-modified tetrahedral DNA nanocage demonstrates high selectivity and safety for anti-tumor therapy

Han et al., 2019

Document ID
16890478326970239600
Author
Han X
Jiang Y
Li S
Zhang Y
Ma X
Wu Z
Wu Z
Qi X
Publication year
Publication venue
Nanoscale

External Links

Snippet

The fabrication of aptamers on DNA nanostructures through the DNA origami method has shown great potential for in vitro and in vivo tumor targeting delivery. Herein, tetrahedral multivalent DNA (Td) nanocages modified with different numbers of MUC1-aptamers (nApt …
Continue reading at pubs.rsc.org (other versions)

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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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