[go: up one dir, main page]

Wolfe et al., 1989 - Google Patents

Assessment of myocardial salvage after ischemia and reperfusion using magnetic resonance imaging and spectroscopy.

Wolfe et al., 1989

View PDF
Document ID
16663713658654409256
Author
Wolfe C
Moseley M
Wikstrom M
Sievers R
Wendland M
Dupon J
Finkbeiner W
Lipton M
Parmley W
Brasch R
Publication year
Publication venue
Circulation

External Links

Snippet

To test the hypothesis that contrast-enhanced magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) can differentiate reversible from irreversible myocardial injury, these modalities were used to study ischemia and reperfusion in a rat …
Continue reading at www.ahajournals.org (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences, Generation or control of pulse sequences ; Operator Console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A61K49/105—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA the metal complex being Gd-DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radiowaves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radiowaves involving electronic or nuclear magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom

Similar Documents

Publication Publication Date Title
Wolfe et al. Assessment of myocardial salvage after ischemia and reperfusion using magnetic resonance imaging and spectroscopy.
Tscholakoff et al. Occlusive and reperfused myocardial infarcts: effect of Gd-DTPA on ECG-gated MR imaging.
McNamara et al. Acute myocardial ischemia: magnetic resonance contrast enhancement with gadolinium-DTPA.
Schmiedl et al. Acute myocardial ischemia and reperfusion: MR imaging with albumin-Gd-DTPA.
Hatabu et al. Pulmonary perfusion: qualitative assessment with dynamic contrast‐enhanced MRI using ultra‐short TE and inversion recovery turbo FLASH
Saeed et al. Reversible and irreversible injury in the reperfused myocardium: differentiation with contrast material-enhanced MR imaging.
Saeed et al. Occlusive and reperfused myocardial infarcts: differentiation with Mn-DPDP--enhanced MR imaging.
Bremerich et al. Normal and infarcted myocardium: differentiation with cellular uptake of manganese at MR imaging in a rat model
JP5456256B2 (en) Cardiac imaging
Van Rossum et al. Value of gadolinium-diethylene-triamine pentaacetic acid dynamics in magnetic resonance imaging of acute myocardial infarction with occluded and reperfused coronary arteries after thrombolysis
Saeed et al. Identification of myocardial reperfusion with echo planar magnetic resonance imaging. Discrimination between occlusive and reperfused infarctions.
Schmiedl et al. Magnetic resonance imaging of myocardial infarction using albumin-(Gd-DTPA), a macromolecular blood-volume contrast agent in a rat model
CN101506679B (en) 13C-MR imaging or spectroscopy of cell death
Roberts et al. MRI of acute myocardial ischemia: Comparing a new contrast agent, Gd‐DTPA‐24‐cascade‐polymer, with Gd‐DTPA
Sievers et al. A model of acute regional myocardial ischemia and reperfusion in the rat
Shukla et al. Regional myocardial oxygen tension: 19F MRI of sequestered perfluorocarbon
Mühler Assessment of myocardial perfusion using contrast-enhanced MR imaging: current status and future developments
Inoue et al. The contributory role of interstitial water in Gd‐DTPA‐enhanced MRI in myocardial infarction
EP0998308B1 (en) Diagnostic method for the detection of miocardial ischemia
Schaefer et al. In vivo nuclear magnetic resonance imaging of myocardial perfusion using the paramagnetic contrast agent manganese gluconate
Rozenman et al. Cardiovascular MR imaging with iron oxide particles: utility of a superparamagnetic contrast agent and the role of diffusion in signal loss.
McNAMARA et al. Magnetic resonance imaging of acute myocardial infarction using a nitroxyl spin label (PCA)
Wyttenbach et al. Detection of acute myocardial ischemia using first‐pass dynamics of MnDPDP on inversion recovery echoplanar imaging
Saeed et al. Dual effects of gadodiamide injection in depiction of the region of myocardial ischemia
Nunnally et al. Flourine-19 NMR spectroscopy and imaging investigations of myocardial perfusion and cardiac function