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Martin-Bouyer et al., 2010 - Google Patents

Cardiovascular effects following epidural injection of romifidine in isoflurane-anaesthetized dogs

Martin-Bouyer et al., 2010

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Document ID
16569381515970135958
Author
Martin-Bouyer V
Schauvliege S
Duchateau L
Bosmans T
Gasthuys F
Polis I
Publication year
Publication venue
Veterinary Anaesthesia and Analgesia

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Objective To investigate the cardiovascular effects of epidural romifidine in isoflurane- anaesthetized dogs. Study design Prospective, randomized, blinded experiment. Animals A total of six healthy adult female Beagles aged 1.25±0.08 years and weighing 12.46±1.48 …
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
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    • A—HUMAN NECESSITIES
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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Martin-Bouyer et al. Cardiovascular effects following epidural injection of romifidine in isoflurane-anaesthetized dogs