[go: up one dir, main page]

Shortle et al., 1998 - Google Patents

Clustering of low-energy conformations near the native structures of small proteins

Shortle et al., 1998

View HTML @Full View
Document ID
14215285566615507791
Author
Shortle D
Simons K
Baker D
Publication year
Publication venue
Proceedings of the National Academy of Sciences

External Links

Snippet

Recent experimental studies of the denatured state and theoretical analyses of the folding landscape suggest that there are a large multiplicity of low-energy, partially folded conformations near the native state. In this report, we describe a strategy for predicting …
Continue reading at www.pnas.org (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/30—Information retrieval; Database structures therefor; File system structures therefor
    • G06F17/30861—Retrieval from the Internet, e.g. browsers
    • G06F17/30864—Retrieval from the Internet, e.g. browsers by querying, e.g. search engines or meta-search engines, crawling techniques, push systems
    • G06F17/30867—Retrieval from the Internet, e.g. browsers by querying, e.g. search engines or meta-search engines, crawling techniques, push systems with filtering and personalisation
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/30—Information retrieval; Database structures therefor; File system structures therefor
    • G06F17/30286—Information retrieval; Database structures therefor; File system structures therefor in structured data stores
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/30—Information retrieval; Database structures therefor; File system structures therefor
    • G06F17/3061—Information retrieval; Database structures therefor; File system structures therefor of unstructured textual data
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • G06F19/16—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for molecular structure, e.g. structure alignment, structural or functional relations, protein folding, domain topologies, drug targeting using structure data, involving two-dimensional or three-dimensional structures
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06Q—DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce, e.g. shopping or e-commerce
    • G06Q30/02—Marketing, e.g. market research and analysis, surveying, promotions, advertising, buyer profiling, customer management or rewards; Price estimation or determination
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06Q—DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTING PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q10/00—Administration; Management
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F21/00—Security arrangements for protecting computers, components thereof, programs or data against unauthorised activity

Similar Documents

Publication Publication Date Title
Shortle et al. Clustering of low-energy conformations near the native structures of small proteins
Norn et al. Protein sequence design by conformational landscape optimization
Ozkan et al. Protein folding by zipping and assembly
Camacho et al. Protein docking along smooth association pathways
McConkey et al. Discrimination of native protein structures using atom–atom contact scoring
Cong et al. Protein interaction networks revealed by proteome coevolution
Xu et al. MDockPeP: An ab‐initio protein–peptide docking server
Zhou et al. Can a continuum solvent model reproduce the free energy landscape of a β-hairpin folding in water?
Krivov et al. Hidden complexity of free energy surfaces for peptide (protein) folding
Tribello et al. A self-learning algorithm for biased molecular dynamics
André et al. Emergence of symmetry in homooligomeric biological assemblies
Shea et al. Exploring the origins of topological frustration: design of a minimally frustrated model of fragment B of protein A
Choi et al. Local feature frequency profile: a method to measure structural similarity in proteins
Jha et al. Statistical coil model of the unfolded state: resolving the reconciliation problem
Zhang et al. On the origin and highly likely completeness of single-domain protein structures
Mackenzie et al. Tertiary alphabet for the observable protein structural universe
Thompson et al. The 3D profile method for identifying fibril-forming segments of proteins
Nepomnyachiy et al. Complex evolutionary footprints revealed in an analysis of reused protein segments of diverse lengths
Sledzieski et al. Democratizing protein language models with parameter-efficient fine-tuning
Teichmann et al. Structural assignments to the Mycoplasma genitalium proteins show extensive gene duplications and domain rearrangements
Street et al. Intrinsic β-sheet propensities result from van der Waals interactions between side chains and the local backbone
Koehl et al. Structure-based conformational preferences of amino acids
Moran et al. The origin of vibrational mode couplings in various secondary structural motifs of polypeptides
Eaton et al. Theory, simulations, and experiments show that proteins fold by multiple pathways
Zhang et al. Automated structure prediction of weakly homologous proteins on a genomic scale