[go: up one dir, main page]

During et al., 2000 - Google Patents

An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy

During et al., 2000

Document ID
12605245713474239899
Author
During M
Symes C
Lawlor P
Lin J
Dunning J
Fitzsimons H
Poulsen D
Leone P
Xu R
Dicker B
Lipski J
Young D
Publication year
Publication venue
Science

External Links

Snippet

The brain is generally considered immunoprivileged, although increasing examples of immunological responses to brain antigens, neuronal expression of major histocompatibility class I genes, and neurological autoimmunity have been recognized. An adeno-associated …
Continue reading at www.science.org (other versions)

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants

Similar Documents

Publication Publication Date Title
During et al. An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy
Gu et al. Myasthenia gravis-like syndrome induced by expression of interferon gamma in the neuromuscular junction.
Flach et al. Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease
Wootla et al. Is multiple sclerosis an autoimmune disease?
Hormigo et al. Immunological and pathological study of anti‐Ri–associated encephalopathy
Darnell et al. Paraneoplastic syndromes involving the nervous system
Linden et al. Physiology of the prion protein
Mabbott et al. Prions and their lethal journey to the brain
Borges et al. Muscle-specific kinase myasthenia gravis
El-Amine et al. Mechanisms of tolerance induction by a gene-transferred peptide-IgG fusion protein expressed in B lineage cells
Ling et al. Traumatic injury and the presence of antigen differentially contribute to T-cell recruitment in the CNS
Sakuma et al. Clinicopathological study of a myelin oligodendrocyte glycoprotein-induced demyelinating disease in LEW. 1AV1 rats
Ludewigs et al. Therapeutic approaches for prion disorders
JP2002535289A (en) Vaccine-mediated treatment of neurological disorders
EA009283B1 (en) Prevention and treatment of amyloidogenic disease
Fontoura et al. Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis
EA013752B1 (en) Prevention and treatment of synucleinopathic and amyloidogenic disease
Horváth et al. IgA autoantibodies in the pemphigoids and linear IgA bullous dermatosis
JP2002508335A (en) Diagnostic and therapeutic agents for infectious spongiform encephalopathy, and methods for producing non-infectious blood products and tissue-derived products
JP2000507232A (en) Vaccine compositions and methods useful for inducing immune protection against arthritogenic peptides required for the pathogenesis of rheumatoid arthritis
Bolton et al. Epitope spreading and autoimmune glomerulonephritis in rats induced by a T cell epitope of Goodpasture’s antigen
Qosa et al. The development of biological therapies for neurological diseases: moving on from previous failures
Myers et al. Peptide‐induced suppression of collagen‐induced arthritis in HLA–DR1 transgenic mice
JP2004511570A (en) Recombinant antibody fragments as autoantibody antagonists
Zhu et al. Rbm8a regulates neurogenesis and reduces Alzheimer’s disease-associated pathology in the dentate gyrus of 5× FAD mice