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Zeng et al., 2018 - Google Patents

Differential phase partition of a PICS complex is required for piRNA processing and chromosome segregation in C. elegans

Zeng et al., 2018

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Document ID
12462722232992366177
Author
Zeng C
Weng C
Wang X
Yan Y
Li W
Xu D
Hong M
Liao S
Feng X
Dong M
Xu C
Guang S
Publication year
Publication venue
bioRxiv

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Snippet

Piwi-interacting RNAs (piRNAs) play significant roles in suppressing transposons and non- self nucleic acids, maintaining genome integrity, defending against viral infections, and are essential for fertility in a variety of organisms. In C. elegans, most piRNA precursors are …
Continue reading at www.biorxiv.org (PDF) (other versions)

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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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Zeng et al. Differential phase partition of a PICS complex is required for piRNA processing and chromosome segregation in C. elegans