[go: up one dir, main page]

Schroff et al., 1985 - Google Patents

Human immune responses to murine monoclonal antibodies

Schroff et al., 1985

Document ID
12381698123302476201
Author
Schroff R
Stevenson H
Publication year
Publication venue
Monoclonal antibody therapy of human cancer

External Links

Snippet

Monoclonal antibodies have great potential for the diagnosis, staging, and therapy of human tumors. As reviewed in the preceding chapters, over a dozen different monoclonal antibodies have been employed for the treatment of advanced malignant diseases since the …
Continue reading at link.springer.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen

Similar Documents

Publication Publication Date Title
Vadhan-Raj et al. Phase I trial of a mouse monoclonal antibody against GD3 ganglioside in patients with melanoma: induction of inflammatory responses at tumor sites.
Weiner et al. Phase I trial of 2B1, a bispecific monoclonal antibody targeting c-erbB-2 and FcγRIII
US8658168B2 (en) Compositions and methods for homoconjugates of antibodies which induce growth arrest of apoptosis of tumor cells
EP2081592B1 (en) Method for generating active antibodies against a resistance antigen, antibodies obtained by said method and their uses
Schultes et al. Anti-idiotype induction therapy: anti-CA125 antibodies (Ab3) mediated tumor killing in patients treated with Ovarex mAb B43. 13 (Ab1)
AU630592B2 (en) Tumor immunotherapy using anti-idiotypic antibodies
Moshly-Rosen et al. Monoclonal antibodies against defined determinants of acetylcholine receptor
WO1992016646A1 (en) Anti-idiotype antibodies to human melanoma-associated proteoglycan antigen
WO1994022478A1 (en) PREVENTION OF TUMORS WITH MONOCLONAL ANTIBODIES AGAINST $i(NEU)
Fagerberg et al. Induction of an immune network cascade in cancer patients treated with monoclonal antibodies (ab1) I. May induction of ab1-reactive T cells and anti-anti-idiotypic antibodies (ab3) lead to tumor regression after mAb therapy?
Schroff et al. Human immune responses to murine monoclonal antibodies
US20030147890A1 (en) Topical treatment of psoriasis using neutralizing antibodies to interleukin-8
Clayman et al. Clonotypic heterogeneity in experimental interstitial nephritis. Restricted specificity of the anti-tubular basement membrane B cell repertoire is associated with a disease-modifying crossreactive idiotype.
Lanier et al. Antigen-induced murine B-cell lymphomas. III. Passive anti-idiotype serum therapy and its combined effect with chemotherapy
JPH11178594A (en) Anti-idiotype monoclonal antibody against Lewis Y-specific monoclonal antibody BR55-2 and use thereof
Giardina et al. Evaluation of alternative methodologies for the generation of murine monoclonal anti-idiotypic antibodies to human B cell leukemias and lymphomas
Austin Doyle et al. Markedly different antibody responses to immunized small cell and non-small cell lung cancer cells
REINSBERG Idiotypic cascades after MAb OC 125 application
CA1339816C (en) Tumor immunotherapy using anti-idiotypic antibodies
Wersäll et al. Induction of a T‐and B‐cell response against a unique amino acid sequence of the mouse IgG2A hinge region in a MAb‐treated patient
Sikora Monoclonal antibodies and drug targeting in cancer
Hanzawa et al. Detection of xenogeneic anti-idiotypic antibodies specific to murine monoclonal antibody 17-1A in patients with gastrointestinal cancer
Maloney B cell malignancy of mouse and man: Exploitation of the surface idiotype as a tumor specific marker
Sikora Department of Clinical Oncology