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Yoo et al., 2008 - Google Patents

Competition potency of siRNA is specified by the 5′-half sequence of the guide strand

Yoo et al., 2008

Document ID
12343437825723959960
Author
Yoo J
Kim S
Lee D
Publication year
Publication venue
Biochemical and biophysical research communications

External Links

Snippet

Small-interfering RNAs (siRNAs) execute specific cellular gene silencing by exploiting the endogenous RNA interference (RNAi) pathway. Therefore, excess amounts of siRNAs can saturate cellular RNAi machineries. Indeed, some siRNAs saturate the RNA-induced …
Continue reading at www.sciencedirect.com (other versions)

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