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Xu et al., 2013 - Google Patents

Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer

Xu et al., 2013

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Document ID
12085864743880965282
Author
Xu W
Siddiqui I
Nihal M
Pilla S
Rosenthal K
Mukhtar H
Gong S
Publication year
Publication venue
Biomaterials

External Links

Snippet

In the absence of effective therapy for prostate cancer, there is an immense need for developing improved therapeutic options for the management of this disease. This study has demonstrated that aptamer-conjugated unimolecular micelles can improve the in vivo tumor …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

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    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
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