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Yang et al., 2019 - Google Patents

CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy

Yang et al., 2019

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Document ID
11315792953613192366
Author
Yang L
Wang S
Ma J
Li J
Yang J
Bucala R
Ren J
Publication year
Publication venue
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease

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CD74, a non-polymorphic type II transmembrane glycoprotein and MHC class II chaperone, is the cell surface receptor for the inflammatory cytokine macrophage migration inhibitory factor (MIF) and participates in inflammatory signaling regulation. This study examined the …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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