[go: up one dir, main page]

Greer et al., 2011 - Google Patents

Mass spectrometry imaging for drugs and metabolites

Greer et al., 2011

View HTML
Document ID
11346867219890027365
Author
Greer T
Sturm R
Li L
Publication year
Publication venue
Journal of proteomics

External Links

Snippet

Mass spectrometric imaging (MSI) is a powerful analytical technique that provides two-and three-dimensional spatial maps of multiple compounds in a single experiment. This technique has been routinely applied to protein, peptide, and lipid molecules with much less …
Continue reading at pmc.ncbi.nlm.nih.gov (HTML) (other versions)

Classifications

    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/0004—Imaging particle spectrometry
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/94—Development

Similar Documents

Publication Publication Date Title
Greer et al. Mass spectrometry imaging for drugs and metabolites
Svatoš Mass spectrometric imaging of small molecules
Rubakhin et al. Imaging mass spectrometry: fundamentals and applications to drug discovery
Kraft et al. Imaging lipids with secondary ion mass spectrometry
Chughtai et al. Mass spectrometric imaging for biomedical tissue analysis
Esquenazi et al. Imaging mass spectrometry of natural products
Hsieh et al. Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry
Spengler Mass spectrometry imaging of biomolecular information
Badu-Tawiah et al. Chemical aspects of the extractive methods of ambient ionization mass spectrometry
US7335897B2 (en) Method and system for desorption electrospray ionization
Stopka et al. Ambient metabolic profiling and imaging of biological samples with ultrahigh molecular resolution using laser ablation electrospray ionization 21 Tesla FTICR mass spectrometry
Chen et al. A high resolution atmospheric pressure matrix-assisted laser desorption/ionization-quadrupole-orbitrap MS platform enables in situ analysis of biomolecules by multi-mode ionization and acquisition
Liu et al. Recent advances in mass spectrometry imaging of single cells
Chen et al. Mapping molecular signatures in plant leaves, flowers, and fruits by a TiO2 nanotube-based plasmonic chip for imprint mass spectrometry imaging
Luo et al. Developing a noncontact heating matrix spraying apparatus with controllable matrix film formation for MALDI mass spectrometry imaging
Zhao et al. Mass spectrometry imaging: applications in drug distribution studies
Ye et al. From pixel to voxel: a deeper view of biological tissue by 3D mass spectral imaging
Pandey Mass Spectrometry: Techniques and Applications
CA2415224A1 (en) Methods for using mass spectrometry to identify and classify filamentous fungi, yeasts, molds and pollen
US20030027231A1 (en) Methods for using mass spectrometry to identify and classify filamentous fungi, yeasts, molds and pollen
Ellis et al. Mass spectrometry imaging of lipids
Snel Ion mobility separation mass spectrometry imaging
Lima et al. Advances in Mass Spectrometry-Metabolomics Based Approaches
Ibáñez et al. Direct mass spectrometry-based approaches in metabolomics
Huan-Wen et al. Principle and Application of Ambient Mass Spectrometry for Direct Analysis of Complex Samples