Gaugg et al., 2016 - Google Patents
Expanding metabolite coverage of real-time breath analysis by coupling a universal secondary electrospray ionization source and high resolution mass spectrometry …Gaugg et al., 2016
View HTML- Document ID
- 11134045732506893039
- Author
- Gaugg M
- Gomez D
- Barrios-Collado C
- Vidal-de-Miguel G
- Kohler M
- Zenobi R
- Sinues P
- Publication year
- Publication venue
- Journal of breath research
External Links
Snippet
Online breath analysis is an attractive approach to track exhaled compounds without sample preparation. Current commercially available real-time breath analysis platforms require the purchase of a full mass spectrometer. Here we present an ion source compatible with …
- 238000004458 analytical method 0 title abstract description 33
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating the ionisation of gases; by investigating electric discharges, e.g. emission of cathode
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Gaugg et al. | Expanding metabolite coverage of real-time breath analysis by coupling a universal secondary electrospray ionization source and high resolution mass spectrometry—a pilot study on tobacco smokers | |
| Bruderer et al. | On-line analysis of exhaled breath: focus review | |
| Smith et al. | Mass spectrometry for real-time quantitative breath analysis | |
| Marzorati et al. | A review of exhaled breath: a key role in lung cancer diagnosis | |
| García-Gómez et al. | Identification of 2-alkenals, 4-hydroxy-2-alkenals, and 4-hydroxy-2, 6-alkadienals in exhaled breath condensate by UHPLC-HRMS and in breath by real-time HRMS | |
| Ruzsanyi et al. | Detection of human metabolites using multi-capillary columns coupled to ion mobility spectrometers | |
| Mbughuni et al. | Mass spectrometry applications for toxicology | |
| Milne et al. | Sum of the parts: mass spectrometry-based metabolomics | |
| Armenta et al. | A review of recent, unconventional applications of ion mobility spectrometry (IMS) | |
| Berchtold et al. | Real‐time monitoring of exhaled drugs by mass spectrometry | |
| Guo et al. | Emerging technologies in mass spectrometry-based DNA adductomics | |
| Bruderer et al. | Detection of volatile organic compounds with secondary electrospray ionization and proton transfer reaction high-resolution mass spectrometry: a feature comparison | |
| Gisler et al. | Real-time breath analysis of exhaled compounds upon peppermint oil ingestion by secondary electrospray ionization-high resolution mass spectrometry: technical aspects | |
| Kleeblatt et al. | Detection of gaseous compounds by needle trap sampling and direct thermal-desorption photoionization mass spectrometry: concept and demonstrative application to breath gas analysis | |
| White et al. | Real-time multi-marker measurement of organic compounds in human breath: towards fingerprinting breath | |
| Zeng et al. | Detection of creatinine in exhaled breath of humans with chronic kidney disease by extractive electrospray ionization mass spectrometry | |
| Lan et al. | Monitoring peppermint washout in the breath metabolome by secondary electrospray ionization-high resolution mass spectrometry | |
| Carrizo et al. | Direct screening of tobacco indicators in urine and saliva by Atmospheric Pressure Solid Analysis Probe coupled to quadrupole-time of flight mass spectrometry (ASAP-MS-Q-TOF-) | |
| Reynolds et al. | Analysis of human breath samples using a modified thermal desorption: gas chromatography electrospray ionization interface | |
| García-Gómez et al. | Real-time high-resolution tandem mass spectrometry identifies furan derivatives in exhaled breath | |
| Pan et al. | Quantitative detection of nitric oxide in exhaled human breath by extractive electrospray ionization mass spectrometry | |
| Gong et al. | Real-time quantitative analysis of valproic acid in exhaled breath by low temperature plasma ionization mass spectrometry | |
| Jazan et al. | Direct analysis of human breath ammonia using corona discharge ion mobility spectrometry | |
| Meurs et al. | Real-time non-invasive monitoring of short-chain fatty acids in exhaled breath | |
| Xie et al. | Analysis of a broad range of carbonyl metabolites in exhaled breath by UHPLC-MS |