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Rosen et al., 1996 - Google Patents

Suramin in hormone-refractory metastatic prostate cancer: a drug with limited efficacy.

Rosen et al., 1996

Document ID
11162999002366990573
Author
Rosen P
Mendoza E
Landaw E
Mondino B
Graves M
McBride J
Turcillo P
deKernion J
Belldegrun A
Publication year
Publication venue
Journal of clinical oncology

External Links

Snippet

PURPOSE To confirm the previously reported high response rates and prolonged survival in hormone-refractory prostate cancer treated with suramin. PATIENTS AND METHODS Thirty- six eligible patients with hormone-refractory prostate cancer with either measurable disease …
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    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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