Simmons et al., 2003 - Google Patents
DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cellsSimmons et al., 2003
View PDF- Document ID
- 10668847325176369790
- Author
- Simmons G
- Reeves J
- Grogan C
- Vandenberghe L
- Baribaud F
- Whitbeck J
- Burke E
- Buchmeier M
- Soilleux E
- Riley J
- Doms R
- Bates P
- Pöhlmann S
- Publication year
- Publication venue
- Virology
External Links
Snippet
Ebola virus exhibits a broad cellular tropism in vitro. In humans and animal models, virus is found in most tissues and organs during the latter stages of infection. In contrast, a more restricted cell and tissue tropism is exhibited early in infection where macrophages, liver …
- 108010037897 DC-specific ICAM-3 grabbing nonintegrin 0 title abstract description 117
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
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- C12N2740/00011—Reverse Transcribing RNA Viruses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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