[go: up one dir, main page]

Wyss et al., 2012 - Google Patents

The elastic properties of valve interstitial cells undergoing pathological differentiation

Wyss et al., 2012

View PDF
Document ID
9861398289800326394
Author
Wyss K
Yip C
Mirzaei Z
Jin X
Chen J
Simmons C
Publication year
Publication venue
Journal of biomechanics

External Links

Snippet

Increasing evidence indicates that the progression of calcific aortic valve disease (CAVD) is influenced by the mechanical forces experienced by valvular interstitial cells (VICs) embedded within the valve matrix. The ability of VICs to sense and respond to tissue-level …
Continue reading at sciencedirect.magic.scholar.google.com (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells

Similar Documents

Publication Publication Date Title
Wyss et al. The elastic properties of valve interstitial cells undergoing pathological differentiation
Merryman et al. Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis
Zhang et al. Long-term mechanical loading is required for the formation of 3D bioprinted functional osteocyte bone organoids
Merryman et al. Synergistic effects of cyclic tension and transforming growth factor-β1 on the aortic valve myofibroblast
Wang et al. Cardiac valve cells and their microenvironment—insights from in vitro studies
Merryman et al. Differences in tissue-remodeling potential of aortic and pulmonary heart valve interstitial cells
Colazzo et al. Extracellular matrix production by adipose-derived stem cells: implications for heart valve tissue engineering
Haugh et al. The role of integrin αVβ3 in osteocyte mechanotransduction
Balachandran et al. An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch
Marinkovic et al. One size does not fit all: developing a cell-specific niche for in vitro study of cell behavior
Myers et al. Osteoblast-like cells and fluid flow: cytoskeleton-dependent shear sensitivity
Perry et al. Bone marrow as a cell source for tissue engineering heart valves
Witkowska‐Zimny et al. Effect of substrate stiffness on the osteogenic differentiation of bone marrow stem cells and bone‐derived cells
Delaine-Smith et al. Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts
Czekanska et al. In search of an osteoblast cell model for in vitro research
Aleshcheva et al. Changes in morphology, gene expression and protein content in chondrocytes cultured on a random positioning machine
Meyer et al. Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression
Grad et al. Sliding motion modulates stiffness and friction coefficient at the surface of tissue engineered cartilage
Boerboom et al. Effect of strain magnitude on the tissue properties of engineered cardiovascular constructs
Poggio et al. Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis
Meyer et al. The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells
Tan et al. Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves
Butcher et al. Equibiaxial strain stimulates fibroblastic phenotype shift in smooth muscle cells in an engineered tissue model of the aortic wall
Hutcheson et al. Intracellular Ca2+ accumulation is strain-dependent and correlates with apoptosis in aortic valve fibroblasts
Sanz-Ramos et al. Response of sheep chondrocytes to changes in substrate stiffness from 2 to 20 Pa: effect of cell passaging