[go: up one dir, main page]

Stanczyk, 2016 - Google Patents

Characterisation of a novel interaction between the cardiac myosin binding protein-C and the ryanodine receptor/calcium release channel

Stanczyk, 2016

View PDF
Document ID
795372970203761261
Author
Stanczyk P
Publication year

External Links

Snippet

Muscle excitation-contraction coupling (ECC) is a fundamental physiological process by which electrically-evoked sarcoplasmic reticulum (SR) Ca2+ release triggers cardiomyocyte contraction. Human ryanodine receptor 2 (RyR2) is an ion channel present in the SR …
Continue reading at orca.cardiff.ac.uk (PDF) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00

Similar Documents

Publication Publication Date Title
van der Ven et al. Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP
WO1998009980A9 (en) Bh3 interacting domain death agonist
AU4411197A (en) Bh3 interacting domain death agonist
KR20210117271A (en) Use of annexin to prevent and treat myofascial injuryUse of annexin to prevent and treat muscle damage
US20080161259A1 (en) Inhibitory pellion nucleic acids
WO2018057648A1 (en) Peptide regulators of mitochondrial fusion and methods of use
WO2002026780A2 (en) Paad domain-containing polypeptides, encoding nucleic acids, and methods of use
US20030077699A1 (en) PAAD domain-containing polypeptides, encoding nucleic acids, and methods of use
CN116981480A (en) Anti-synucleinopathy peptides and methods for treating neurodegenerative diseases
US20110189711A1 (en) Paad domain-containing polypeptides, encoding nucleic acids, and methods of use
Stanczyk Characterisation of a novel interaction between the cardiac myosin binding protein-C and the ryanodine receptor/calcium release channel
US20110086089A1 (en) Use of p27kip1 for the prevention and treatment of heart failure
AU756370B2 (en) Myotilin, an actin-organizing protein
Zallocchi et al. Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells
JP2021507680A (en) Calcium chelated peptide derived from EF hand calcium binding motif
US20100317598A1 (en) Isolated BRCA1 Peptides and Method of Use
Axelrod Investigations into Mitochondrial Cell Death Mechanisms in Myocardial Infarction
Young Turning Autophagy On and Off through the Class III PI-3 Kinase
Cooley Dysregulated Membrane Trafficking and the Development of Pancreatitis
Nougarede Molecular basis of BCL2L10/Nrh oncogenic activity in breast cancer
Gorski Molecular insights into SERCA regulation by endogenous peptide modulators
Thomas Molecular mechanisms underlying cardiac ryanodine receptor dysfunction in sudden cardiac death.
Wang Multifaceted Regulation of Neuronal L-Type Ca2+ Channels by the N-Terminal Domain: from CaMKII Targeting to Nuclear Signaling
Desmond Identification of Small Ankyrin 1 as a novel SERCA1 regulatory protein in Skeletal Muscle
Evans Spastin, a microtubule severing enzyme, interacts with Atlastin: Two HSP genes suggesting a common pathway for axonal maintenance