Qiu et al., 2019 - Google Patents
BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disordersQiu et al., 2019
View HTML- Document ID
- 6695184543511336617
- Author
- Qiu P
- Jiang J
- Liu Z
- Cai Y
- Huang T
- Wang Y
- Liu Q
- Nie Y
- Liu F
- Cheng J
- Li Q
- Tang Y
- Poo M
- Sun Q
- Chang H
- Publication year
- Publication venue
- National Science Review
External Links
Snippet
Circadian disruption is a risk factor for metabolic, psychiatric and age-related disorders, and non-human primate models could help to develop therapeutic treatments. Here, we report the generation of BMAL1 knockout cynomolgus monkeys for circadian-related disorders by …
- 101710016789 ARNTL 0 title abstract description 81
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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