[go: up one dir, main page]

Schuhmacher, 2019 - Google Patents

Identification of antibiotic agents directed against gram-negative bacteria by exploiting interspecies communication

Schuhmacher, 2019

View PDF
Document ID
6529697676232759718
Author
Schuhmacher T
Publication year

External Links

Snippet

Arising antibiotic resistances in bacteria pose a major global threat resulting in increased morbidi-ty, mortality and healthcare costs. Recently, the WHO stressed the need to develop new antibac-terial strategies and discover novel bactericidal compounds to turn the tides in …
Continue reading at kops.uni-konstanz.de (PDF) (other versions)

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients

Similar Documents

Publication Publication Date Title
MacAlpine et al. Bacterial‐fungal interactions and their impact on microbial pathogenesis
Parai et al. Effect of reserpine on Pseudomonas aeruginosa quorum sensing mediated virulence factors and biofilm formation
Liu et al. Plasmid-encoded Pgp3 is a major virulence factor for Chlamydia muridarum to induce hydrosalpinx in mice
Lin et al. The icmF3 locus is involved in multiple adaptation-and virulence-related characteristics in Pseudomonas aeruginosa PAO1
O'Grady et al. The Burkholderia cenocepacia LysR-type transcriptional regulator ShvR influences expression of quorum-sensing, protease, type II secretion, and afc genes
Schmitt et al. Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo
Di Marco et al. Aporphinoid alkaloids inhibit biofilm formation of Yersinia enterocolitica isolated from sausages
Lin et al. Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin
Yin et al. Tyramine, one quorum sensing inhibitor, reduces pathogenicity and restores tetracycline susceptibility in Burkholderia cenocepacia
Zhai et al. Evaluation of the anticryptococcal activity of the antibiotic polymyxin B in vitro and in vivo
Chen et al. Novel inhibition of Staphylococcus aureus sortase A by plantamajoside: implications for controlling multidrug-resistant infections
Shao et al. Application and mechanism of cryptolepine and neocryptolepine derivatives as T3SS inhibitors for control of bacterial leaf blight on rice
Bajire et al. 7-Ethoxycoumarin rescued Caenorhabditis elegans from infection of COPD derived clinical isolate Pseudomonas aeruginosa through virulence and biofilm inhibition via targeting Rhl and Pqs quorum sensing systems
Zhang et al. 2-Chloromethyl anthraquinone inhibits Candida albicans biofilm formation by inhibiting the Ras1-cAMP-Efg1 pathway
Tan Abundant monovalent ions as environmental signposts for pathogens during host colonization
Arita et al. Serial systemic candidiasis alters Candida albicans macromorphology associated with enhancement of virulence attributes
Jiang et al. In vitro and in vivo evaluation of the antifungal activity of fluoxetine combined with antifungals against Candida albicans biofilms and oral candidiasis
Bleem et al. Designed α-sheet peptides disrupt uropathogenic E. coli biofilms rendering bacteria susceptible to antibiotics and immune cells
Lian et al. Deficiency of the flagellin subunit FliC exacerbates the pathogenicity of extraintestinal pathogenic Escherichia coli in BALB/c mice by inducing a more intense inflammation
Schuhmacher Identification of antibiotic agents directed against gram-negative bacteria by exploiting interspecies communication
Schuhmacher et al. Identification of antibiotic agents directed against gram-negative bacteria by exploiting interspecies communication
US20250025528A1 (en) Materials and methods for preventing or reducing toxicity to organophosphates and other toxic materials
González et al. Urinary tract infection: is it time for a new approach considering a gender perspective and new microbial advances?
Georges et al. Understanding current challenges of antibiotic resistance to find new solutions for 2050: scientific, medical and political issues
Li et al. Protease SfpB plays an important role in cell membrane stability and immune system evasion in Streptococcus agalactiae