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Lin et al., 2014 - Google Patents

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response

Lin et al., 2014

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Document ID
6406810106499326637
Author
Lin Y
Shih H
Shang Z
Matsunaga S
Chen B
Publication year
Publication venue
Nucleic Acids Research

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The ataxia telangiectasia mutated and Rad3-related (ATR)-checkpoint kinase 1 (Chk1) axis is the major signaling pathway activated in response to replication stress and is essential for the intra-S checkpoint. ATR phosphorylates and activates a number of molecules to …
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    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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