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Sevcik et al., 2012 - Google Patents

The BRCA1 alternative splicing variant Δ14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in …

Sevcik et al., 2012

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Document ID
6120726600673247802
Author
Sevcik J
Falk M
Kleiblova P
Lhota F
Stefancikova L
Janatova M
Weiterova L
Lukasova E
Kozubek S
Pohlreich P
Kleibl Z
Publication year
Publication venue
Cellular signalling

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The BRCA1 gene codes for a protein involved in the DNA double strand break (DDSB) repair. Alongside the dominant full-length splicing form of BRCA1, numerous endogenously expressed alternative splicing variants of unknown significance have been described in …
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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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