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Zhuang et al., 2011 - Google Patents

WNK4 kinase inhibits Maxi K channel activity by a kinase-dependent mechanism

Zhuang et al., 2011

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Document ID
5900154881643837394
Author
Zhuang J
Zhang X
Wang D
Li J
Zhou B
Shi Z
Gu D
Denson D
Eaton D
Cai H
Publication year
Publication venue
American Journal of Physiology-Renal Physiology

External Links

Snippet

WNK [with no lysine (k)] kinase is a serine/threonine kinase subfamily. Mutations in two of the WNK kinases result in pseudohypoaldosteronism type II (PHA II) characterized by hypertension, hyperkalemia, and metabolic acidosis. Recent studies showed that both …
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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