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Liu et al., 2025 - Google Patents

OMEGA-guided DNA polymerases enable random mutagenesis in a tunable window

Liu et al., 2025

Document ID
5757147918381159037
Author
Liu L
Lei W
Zhang Z
Lai S
Xu B
Ge Q
Luo J
Yang M
Zhang Y
Chen J
Zhong Q
Wu Y
Jiang A
Publication year
Publication venue
Trends in Biotechnology

External Links

Snippet

Targeted random mutagenesis is crucial for breeding, directed evolution, and gene function studies, yet efficient tools remain scarce. Here, we present obligate mobile element guided activity (OMEGA)-R, an innovative targeted random mutagenesis system that integrates …
Continue reading at www.cell.com (other versions)

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