[go: up one dir, main page]

Gill et al., 1998 - Google Patents

Resolution of isobaric and isomeric ions using chemical shifts in an ion trap mass spectrometer

Gill et al., 1998

View PDF
Document ID
5578403847355363175
Author
Gill L
Wells J
Patterson G
Amy J
Cooks R
Publication year
Publication venue
Analytical Chemistry

External Links

Snippet

Isobaric and isomeric polyatomic ions are resolved for the first time in a quadrupole ion trap. This is achieved using a trap in which the geometry of the instrument can be manipulated under operating conditions. Variation of the zo dimension of the trap allows the chemical …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping
    • H01J49/4215—Quadrupole mass filters
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/36—Radio frequency spectrometers, e.g. Bennett-type spectrometers, Redhead-type spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating the ionisation of gases; by investigating electric discharges, e.g. emission of cathode
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Similar Documents

Publication Publication Date Title
Dodds et al. Correlating resolving power, resolution, and collision cross section: unifying cross-platform assessment of separation efficiency in ion mobility spectrometry
Easterling et al. Routine part-per-million mass accuracy for high-mass ions: space-charge effects in MALDI FT-ICR
Badman et al. A parallel miniature cylindrical ion trap array
Marshall et al. High-resolution mass spectrometers
Delvaux et al. Different ion mobility‐mass spectrometry coupling techniques to promote metabolomics
Tang et al. High-sensitivity ion mobility spectrometry/mass spectrometry using electrodynamic ion funnel interfaces
Zubarev et al. Orbitrap mass spectrometry
Savaryn et al. A researcher's guide to mass spectrometry‐based proteomics
Nagy et al. Distinguishing enantiomeric amino acids with chiral cyclodextrin adducts and structures for lossless ion manipulations
Xian et al. High resolution mass spectrometry
Badman et al. Cylindrical ion trap array with mass selection by variation in trap dimensions
Wells et al. Chemical mass shifts in ion trap mass spectrometry: experiments and simulations
Junot et al. Fourier transform mass spectrometry for metabolome analysis
Xu et al. Pseudo-multiple reaction monitoring (pseudo-MRM) mode on the “brick” mass spectrometer, using the grid-SWIFT waveform
Solouki et al. Gas-phase hydrogen/deuterium exchange reactions of fulvic acids: an electrospray ionization Fourier transform ion cyclotron resonance mass spectral study
Shaw et al. High speed intact protein characterization using 4X frequency multiplication, ion trap harmonization, and 21 Tesla FTICR-MS
Qi et al. Phase correction of Fourier transform ion cyclotron resonance mass spectra using MatLab
Soni et al. Broad-band Fourier transform quadrupole ion trap mass spectrometry
Cleven et al. Radial distributions and ejection times of molecular ions in an ion trap mass spectrometer: a laser tomography study of effects of ion density and molecular type
Barbier Saint Hilaire et al. Evaluation of the high-field Orbitrap fusion for compound annotation in metabolomics
Park et al. Parallel detection of fundamental and sixth harmonic signals using an ICR cell with dipole and sixth harmonic detectors
Smith et al. Ultrahigh resolution ion isolation by stored waveform inverse Fourier transform 21 T Fourier transform ion cyclotron resonance mass spectrometry
Davis et al. Optimized reconstruction techniques for multiplexed dual-gate ion mobility mass spectrometry experiments
Conant et al. Evaluation of waveform profiles for traveling wave ion mobility separations in structures for lossless ion manipulations
Gill et al. Resolution of isobaric and isomeric ions using chemical shifts in an ion trap mass spectrometer