[go: up one dir, main page]

Helmja et al., 2009 - Google Patents

Fraction collection in capillary electrophoresis for various stand-alone mass spectrometers

Helmja et al., 2009

View PDF
Document ID
552043039792691636
Author
Helmja K
Borissova M
Knjazeva T
Jaanus M
Muinasmaa U
Kaljurand M
Vaher M
Publication year
Publication venue
Journal of Chromatography A

External Links

Snippet

A procedure for collecting fractions during capillary electrophoresis for their analysis using various stand-alone instruments is described. The results of a systematic study of the optimization and application of capillary electrophoresis (CE) in conjunction with a reverse …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or superfluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/30—Control of physical parameters of the fluid carrier of temperature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/94—Development
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating the ionisation of gases; by investigating electric discharges, e.g. emission of cathode
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns

Similar Documents

Publication Publication Date Title
Jemal High‐throughput quantitative bioanalysis by LC/MS/MS
Schmitt‐Kopplin et al. Capillary electrophoresis–mass spectrometry: 15 years of developments and applications
Ramautar et al. CE‐MS in metabolomics
Staub et al. CE‐TOF/MS: fundamental concepts, instrumental considerations and applications
WO2008118808A1 (en) Liquid chromatography-mass spectrometry
Bruins et al. On-line coupling of solid-phase extraction with mass spectrometry for the analysis of biological samples: I. Determination of clenbuterol in urine
Song et al. Determination of chlorinated acid herbicides and related compounds in water by capillary electrophoresis–electrospray negative ion mass spectrometry
US20170097320A1 (en) Multi-segment injection-capillary electrophoresis-mass spectrometry (msi-ce-ms): a multiplexed screening platform and data workflow for chemical analysis
Wu et al. On-line analysis by capillary separations interfaced to an ion trap storage/reflectron time-of-flight mass spectrometer
Janini et al. Two‐dimensional liquid chromatography‐capillary zone electrophoresis‐sheathless electrospray ionization‐mass spectrometry: Evaluation for peptide analysis and protein identification
Huck et al. Analysis of three flavonoids by CE‐uV and CE‐ESI‐MS. Determination of naringenin from a phytomedicine
WO2015175561A1 (en) Quantitation of tamoxifen and metabolites thereof by mass spectrometry
Helmja et al. Fraction collection in capillary electrophoresis for various stand-alone mass spectrometers
Crowley et al. Analysis of human blood serum using the off‐line coupling of capillary isoelectric focusing to matrix‐assisted laser desorption/ionization time of flight mass spectrometry
CN104833761A (en) Method for quickly analyzing carbohydrates in samples
CN105092733B (en) The reduction method and apparatus of fixedness buffer salt content in LC MS testers
KR20210117267A (en) Automated Sample Workflow for LC-MS-Based HbA1c Determination of Circular Protein Levels
De la Guardia et al. Multianalyte determination versus one-at-a-time methodologies
Plumb et al. The application of fast gradient capillary liquid chromatography/mass spectrometry to the analysis of pharmaceuticals in biofluids
EP3861351B1 (en) Methods and systems for measuring ascorbic acid
Welters et al. Coupling Capillary Electrophoresis With a Shifted Inlet Potential High‐Resolution Ion Mobility Spectrometer
Meermann et al. Iodine speciation using thin-layer chromatography coupled to inductively coupled plasma-mass spectrometry by means of an extraction device
Sladkovský et al. Off-line coupling of isotachophoresis and high performance liquid chromatography for determination of flavonoids in plant extract
Phale et al. Current advance analytical techniques: a review
Lu et al. On‐line concentration of neomycin and screening aminoglycosides in milk by short capillary column and tandem mass spectrometry