Cortez et al., 2017 - Google Patents
Aged dominant negative p38α MAPK mice are resistant to age-dependent decline in adult-neurogenesis and context discrimination fear conditioningCortez et al., 2017
View PDF- Document ID
- 5402454006696600379
- Author
- Cortez I
- Bulavin D
- Wu P
- McGrath E
- Cunningham K
- Wakamiya M
- Papaconstantinou J
- Dineley K
- Publication year
- Publication venue
- Behavioural brain research
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A major aspect of mammalian aging is the decline in functional competence of many self- renewing cell types, including adult-born neuronal precursors. Since age-related senescence of self-renewal occurs simultaneously with chronic up-regulation of the …
- 230000001419 dependent 0 title abstract description 25
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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