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Gulyas et al., 1992 - Google Patents

SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3

Gulyas et al., 1992

Document ID
4991903901326050815
Author
Gulyas K
Donahue T
Publication year
Publication venue
Cell

External Links

Snippet

Reversion of haploid, Hisrl-yeast containing a stemloop mutation in the 5'UTR that blocks HIS4 translation initiation identified four unlinked suppressor genes, SSLf-SSL4, which restore His4+ expression. The SSLP gene encodes an essential 95 kd protein with ATP …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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