Wang et al., 2005 - Google Patents
Chemoenzymatic synthesis of HIV‐1 gp41 glycopeptides: effects of glycosylation on the anti‐HIV activity and α‐helix bundle‐forming ability of peptide C34Wang et al., 2005
- Document ID
- 4987203636052033734
- Author
- Wang L
- Song H
- Liu S
- Lu H
- Jiang S
- Ni J
- Li H
- Publication year
- Publication venue
- ChemBioChem
External Links
Snippet
C34 is a 34‐mer peptide derived from the C‐terminal ectodomain of HIV‐1 envelope glycoprotein, gp41. The C34 region in native gp41 carries a conserved N‐glycan at Asn637 and the sequence is directly involved in the virus–host membrane fusion, an essential step …
- 238000003786 synthesis reaction 0 title abstract description 31
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse Transcribing RNA Viruses
- C12N2740/00011—Reverse Transcribing RNA Viruses
- C12N2740/10011—Retroviridae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Wang et al. | Chemoenzymatic synthesis of HIV‐1 gp41 glycopeptides: effects of glycosylation on the anti‐HIV activity and α‐helix bundle‐forming ability of peptide C34 | |
| US12146880B2 (en) | Artificial transcription factors comprising a sliding domain and uses thereof | |
| Go et al. | Glycosylation site-specific analysis of hiv envelope proteins (jr-fl and con-s) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopesʼ accessibility | |
| Braun et al. | Chemical characterization, spatial distribution and function of a lipoprotein (murein‐lipoprotein) of the E. coli cell wall: the specific effect of trypsin on the membrane structure | |
| EP2267452B1 (en) | A soluble complex comprising a retroviral surface glycoprotein | |
| Martínez‐Ávila et al. | Gold manno‐glyconanoparticles: Multivalent systems to block HIV‐1 gp120 binding to the lectin DC‐SIGN | |
| Ni et al. | Synthesis of maleimide-activated carbohydrates as chemoselective tags for site-specific glycosylation of peptides and proteins | |
| Go et al. | Glycosylation site-specific analysis of clade C HIV-1 envelope proteins | |
| Horiya et al. | Directed evolution of multivalent glycopeptides tightly recognized by HIV antibody 2G12 | |
| Toonstra et al. | Top-down chemoenzymatic approach to synthesizing diverse high-mannose N-glycans and related neoglycoproteins for carbohydrate microarray analysis | |
| Matsushita et al. | Construction of highly glycosylated mucin-type glycopeptides based on microwave-assisted solid-phase syntheses and enzymatic modifications | |
| Huang et al. | Enzymatic Glycosylation of Triazole‐Linked GlcNAc/Glc–Peptides: Synthesis, Stability and Anti‐HIV Activity of Triazole‐Linked HIV‐1 gp41 Glycopeptide C34 Analogues | |
| JPH08507686A (en) | Genetically engineered enzymes and their conjugates for diagnostic assays | |
| Wehofsky et al. | Ionic liquids and proteases: A clean alliance for semisynthesis | |
| Marra et al. | Protein glycosylation through sulfur fluoride exchange (sufex) chemistry: The key role of a fluorosulfate thiolactoside | |
| Yuan et al. | Characterization of the calmodulin binding domain of SIV transmembrane glycoprotein by NMR and CD spectroscopy | |
| Real Fernández et al. | Antibody recognition in multiple sclerosis and Rett syndrome using a collection of linear and cyclic N‐glucosylated antigenic probes | |
| EP1738764A1 (en) | Glycopeptides of the V3 loop of gp120 and derivatives; preparation and applications as HIV-1 vaccines. | |
| Moyer et al. | Leveraging orthogonal mass spectrometry based strategies for comprehensive sequencing and characterization of ribosomal antimicrobial peptide natural products | |
| DE3850593T2 (en) | Synthetic antigens for the determination of AIDS-related diseases caused by LAV-2. | |
| Wang et al. | De novo design of isopeptide bond-tethered triple-stranded coiled coils with exceptional resistance to unfolding and proteolysis: implication for developing antiviral therapeutics | |
| Chen et al. | Neoglycoproteins: preparation and properties of complexes of biotinylated asparagine-oligosaccharides with avidin and streptavidin | |
| Astoul et al. | Accessibility of the high-mannose glycans of glycoprotein gp120 from human immunodeficiency virus type 1 probed by in vitro interaction with mannose-binding lectins | |
| Fernández et al. | Synthetic peptides derived from an N‐terminal domain of the E2 protein of GB virus C in the study of GBV‐C/HIV‐1 co‐infection | |
| Pashov et al. | Defining carbohydrate antigens as HIV vaccine candidates |