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Liem‐Moolenaar et al., 2013 - Google Patents

Early stage development of the glycine‐1 re‐uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men

Liem‐Moolenaar et al., 2013

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Document ID
4048957786970407775
Author
Liem‐Moolenaar M
Peeters P
Kamerling I
Hogg C
Holder G
Kleijn H
Spaans E
Udo De Haes J
de Kam M
Franson K
Cohen A
van Gerven J
Publication year
Publication venue
British journal of clinical pharmacology

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Snippet

Aims To report the first three studies with SCH 900435, a selective glycine‐1 re‐uptake inhibitor in development for treating schizophrenia, using systematic evaluations of pharmacodynamics to understand the observed effects. Methods Three double‐blind …
Continue reading at bpspubs.onlinelibrary.wiley.com (PDF) (other versions)

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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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