The Rosetta Bio-macromolecule modeling package.

This repo contains the codes for our paper "End-to-End Full-Atom Antibody Design"

This repo contains the codes for our paper Conditional Antibody Design as 3D Equivariant Graph Translation.

Improved antibody structure-based design using inverse folding

The official implementation of DiffAbXL benchmarked in the paper "Exploring Log-Likelihood Scores for Ranking Antibody Sequence Designs", formerly titled "Benchmarking Generative Models for Antibody Design".

This is the official repository of paper - GeoAB: Towards Realistic Antibody Design and Reliable Affinity Maturation (ICML2024)

An antibody-specific language model focusing on NGL prediction

A Collection of Platform, Tools, and Resources for Antibody Engineering

The official implementation of "Improving Antibody Humanness Prediction using Patent Data".

PD-1 Targeted Antibody Discovery Using AI Protein Diffusion

Antibody optimization platform

Protein structure handling in Python made easy.

Gradient guided discrete walk-jump sampling

An unofficial re-implementation of DiffAb, a diffusion-based generative model for antigen-specific antibody design and optimization.

Characterizing Broadly Neutralizing Antibody Maturation Pathways Using Reinforcement Learning

Code for Opponent Shaping for Antibody Development

DeepBioLab is an AI-focused platform designed to explore, build, and share advanced AI algorithms. It features educational content, projects, and research on topics like deep learning, reinforcement learning, and more. Dive into algorithms, develop from scratch, and discover solutions to science problems.

This repository contains codes for the regeneration of figures 3b and 3g in Tam, C., Kukimoto-Niino, M., Miyata-Yabuki, Y. et al. Targeting Ras-binding domain of ELMO1 by computational nanobody design. Commun Biol 6, 284 (2023).