FGF9

FGF9
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1G82, 1IHK
Dynodwyr
Cyfenwau	FGF9, FGF-9, GAF, HBFG-9, HBGF-9, SYNS3, fibroblast growth factor 9
Dynodwyr allanol	OMIM: 600921 HomoloGene: 1523 GeneCards: FGF9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • heparin binding • fibroblast growth factor receptor binding • protein tyrosine kinase activity • phosphatidylinositol-4,5-bisphosphate 3-kinase activity • 1-phosphatidylinositol-3-kinase activity • growth factor activity Cydrannau o'r gell • cytoplasm • extracellular region • basement membrane • extracellular exosome • extracellular space Prosesau biolegol • eye development • positive regulation of vascular endothelial growth factor receptor signaling pathway • cell differentiation • male gonad development • chondrocyte differentiation • substantia nigra development • protein import into nucleus • positive regulation of smoothened signaling pathway • regulation of timing of cell differentiation • positive regulation of epithelial cell proliferation • lung development • positive regulation of canonical Wnt signaling pathway • negative regulation of Wnt signaling pathway • GO:1901227 negative regulation of transcription by RNA polymerase II • male sex determination • MAPK cascade • embryonic skeletal system development • multicellular organism development • GO:1901313 positive regulation of gene expression • positive regulation of activin receptor signaling pathway • positive regulation of cardiac muscle cell proliferation • positive regulation of mesenchymal cell proliferation • embryonic limb morphogenesis • inner ear morphogenesis • angiogenesis • osteoblast differentiation • positive regulation of cell population proliferation • lung-associated mesenchyme development • embryonic digestive tract development • positive regulation of cell division • GO:0072468 signal transduction • positive regulation of MAPK cascade • phosphatidylinositol phosphate biosynthetic process • fibroblast growth factor receptor signaling pathway • cell-cell signaling • phosphatidylinositol-3-phosphate biosynthetic process • peptidyl-tyrosine phosphorylation • regulation of signaling receptor activity • positive regulation of protein kinase B signaling • regulation of molecular function • positive regulation of vascular associated smooth muscle cell proliferation • positive regulation of vascular associated smooth muscle cell migration • negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2254	n/a
Ensembl	ENSG00000102678	n/a
UniProt	P31371	n/a
RefSeq (mRNA)	NM_002010	n/a
RefSeq (protein)	NP_002001	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FGF9 yw FGF9 a elwir hefyd yn Fibroblast growth factor 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 13, band 13q12.11.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FGF9.

• "The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer. ". Oncotarget. 2016. PMID 27166269.
• "Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases. ". J Biol Chem. 2015. PMID 26183774.
• "FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells. ". BMC Cancer. 2015. PMID 25925261.
• "Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation. ". Nucleic Acids Res. 2014. PMID 24334956.
• "Expression of fibroblast growth factor 9 is associated with poor prognosis in patients with resected non-small cell lung cancer.". Lung Cancer. 2014. PMID 24239165.