There are 4 ways to get from Mayo Clinic to Rapid City by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rochester
best- Fly from Rochester (RST) to Rapid City (RAP)plane RST - RAP
6h 12m$77–423Bus
- Take the bus from Rochester to Minneapolisbus Jefferson Lines 966
- Take the bus from Minneapolis to Rapid Citybus Jefferson Lines 701
15h 18m$171–242Drive 573.7 mi
- Drive from Mayo Clinic to Rapid Citycar 573.7 mi
8h 38m$105–152Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Rapid City (RAP)plane MSP - RAP
5h 25m$136–516
Mayo Clinic to Rapid City by foot and bus
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Rapid City is to drive which costs $100 - $160 and takes 8h 38m.
The fastest way to get from Mayo Clinic to Rapid City is to bus and fly which takes 5h 25m and costs $130 - $550.
No, there is no direct bus from Mayo Clinic to Rapid City. However, there are services departing from Rochester and arriving at Rapid City via Minneapolis. The journey, including transfers, takes approximately 15h 18m.
The distance between Mayo Clinic and Rapid City is 548 miles. The road distance is 577.1 miles.
The best way to get from Mayo Clinic to Rapid City without a car is to bus which takes 15h 18m and costs $170 - $250.
It takes approximately 6h 12m to get from Mayo Clinic to Rapid City, including transfers.
Mayo Clinic to Rapid City bus services, operated by Jefferson Lines, depart from Rochester station.
The best way to get from Mayo Clinic to Rapid City is to fly which takes 6h 12m and costs $75 - $430. Alternatively, you can bus, which costs $170 - $250 and takes 15h 18m.
Mayo Clinic to Rapid City bus services, operated by Jefferson Lines, arrive at Minneapolis station.
Yes, the driving distance between Mayo Clinic to Rapid City is 577 miles. It takes approximately 8h 38m to drive from Mayo Clinic to Rapid City.
What companies run services between Mayo Clinic, MN, USA and Rapid City, SD, USA?
Delta and American Airlines fly from Rochester (RST) to Rapid City (RAP) 5 times a day. Alternatively, you can take a vehicle from Mayo Clinic to Rapid City via Rochester and Minneapolis in around 15h 18m.
- Website
- delta.com
Flights from Rochester to Rapid City via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $65–370
Flights from Minneapolis–Saint Paul International Airport to Rapid City
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $75–450
- Website
- aa.com
Flights from Rochester to Rapid City via Chicago O'Hare
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $90–460
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Minneapolis
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Minneapolis to Rapid City
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $140–200
- Book at
- Jefferson Lines
- Adult
- $140–200
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
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