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How to get fromMayo Clinic to Royal Oakby plane, bus (Flixbus), bus, train, car, or bus (Amtrak)

Find Transport to Royal Oak

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There are 8 ways to get from Mayo Clinic to Royal Oak by plane, bus (Flixbus), bus, train, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Detroit

    best
    1. Fly from Rochester (RST) to Detroit (DTW)plane plane RST - DTW
    8h 16m
    $94–546

  2. Bus

    1. Take the bus from Rochester to Milwaukeebus bus Jefferson Lines 965
    2. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus bus FlixBus 2550
    15h 32m
    $127–183

  3. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Royal Oak Amtraktrain train
    16h 54m
    $409–639

  4. Drive  627.2 mi

    1. Drive from Mayo Clinic to Royal Oakcar car 627.2 mi
    10h 27m
    $115–166

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Detroit, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)plane plane MSP - DTW
    3. Take the train from Dearborn to Royal Oak Amtraktrain train
    6h 48m
    $663–1,269

  6. Fly Rochester to Bishop International Airport, bus

    1. Fly from Rochester (RST) to Bishop International Airport (FNT)plane plane RST - FNT
    2. Take the bus from Flint to Pontiacbus bus
    8h 40m
    $109–474

  7. Bus via Chicago

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Royal Oak Amtrakbus bus
    15h 43m

  8. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Royal Oak Amtraktrain train
    15h 43m
    $240–384

Mayo Clinic to Royal Oak by foot and bus

Calendar4Weekly Services
Duration15h 32mAverage Duration
Ticket$127Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mayo Clinic to Royal Oak.ExpandLaunch map view
  • Distance: 517.1 mi
  • Duration: 8h 16m

What companies run services between Mayo Clinic, MN, USA and Royal Oak, MI, USA?

American Airlines and Delta fly from Rochester (RST) to Detroit (DTW) every 3 hours. Alternatively, you can take a vehicle from Mayo Clinic to Woodward & Hendrie via Rochester, Milwaukee, Milwaukee Intermodal Station, Detroit Bus Station, and Jefferson & Griswold in around 15h 32m.

Airlines
Train operators
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