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How to get fromBirmingham to Mayo Clinicby plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound, Amtrak)

Find Transport to Mayo Clinic

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There are 8 ways to get from Birmingham to Mayo Clinic by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Birmingham–Shuttlesworth International Airport to Rochester

    best
    1. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Rochester (RST)plane plane BHM - RST
    6h 58m
    $106–548

  2. Bus

    1. Take the bus from Birmingham Intermodal Facility to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    23h 38m
    $184–291

  3. Drive  915 mi

    1. Drive from Birmingham to Mayo Cliniccar car 915 mi
    16h 20m
    $167–242

  4. Fly Birmingham–Shuttlesworth International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Birmingham–Shuttlesworth International Airport (BHM) to Minneapolis–Saint Paul International Airport (MSP)plane plane BHM - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 28m
    $175–718

  5. Drive to Huntsville International Airport-Carl T Jones Field, fly to Rochester

    1. Drive from Birmingham to Huntsville International Airport-Carl T Jones Field (HSV)car car
    2. Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Rochester (RST)plane plane HSV - RST
    8h
    $112–613

  6. Bus, train via Carbondale

    1. Take the bus from Birmingham Intermodal Facility to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the train from Carbondale to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Milwaukeetrain train
    5. Take the bus from Milwaukee to Rochesterbus bus
    23h 52m
    $346–543

  7. Bus via Lafayette

    1. Take the bus from Birmingham Intermodal Facility to Nashville Bus Stationbus bus
    2. Take the bus from Nashville to Lafayette Amtrak Stationbus bus
    3. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    4. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    5. Take the bus from Madison to Rochesterbus bus
    24h 36m
    $180–293

  8. Bus, train

    1. Take the bus from Birmingham Intermodal Facility to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    27h 31m
    $260–432

Birmingham to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration23h 38mAverage Duration
Ticket$184Cheapest Price
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Comparing Your Travel Options

Map of how to get from Birmingham to Mayo Clinic.ExpandLaunch map view
  • Distance: 792.6 mi
  • Duration: 6h 58m

What companies run services between Birmingham, AL, USA and Mayo Clinic, MN, USA?

American Airlines, United Airlines, and Delta fly from Birmingham–Shuttlesworth International Airport (BHM) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Birmingham Intermodal Facility to Mayo Clinic via Nashville Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 23h 38m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

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