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How to get fromSavannah to Mayo Clinicby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Mayo Clinic

See all options

There are 6 ways to get from Savannah to Mayo Clinic by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Savannah (SAV) to Rochester (RST)plane plane SAV - RST
    6h 44m
    $174–740
  2. Bus

    1. Take the bus from Savannah Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    30h 39m
    $220–375
  3. Train, bus via Madison

    1. Take the train from Savannah Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    41h 50m
    $855–1,327
  4. Drive  1,247.1 mi

    1. Drive from Savannah to Mayo Cliniccar car 1,247.1 mi
    21h 25m
    $228–329
  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Savannah (SAV) to Minneapolis–Saint Paul International Airport (MSP)plane plane SAV - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 29m
    $253–950
  6. Train, bus

    1. Take the train from Savannah Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    43h 8m
    $1,028–1,587

Savannah to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration30h 39mAverage Duration
Ticket$220Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Savannah, GA, USA and Mayo Clinic, MN, USA?

Delta, United Airlines, and American Airlines fly from Savannah (SAV) to Rochester (RST) 3 times a day. Alternatively, you can take a bus from Savannah Bus Station to Mayo Clinic via Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 30h 39m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There