There are 6 ways to get from Appleton to Des Moines by plane, bus (Greyhound, Flixbus), car, taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Appleton International Airport
best- Fly from Appleton International Airport (ATW) to Des Moines (DSM)plane ATW - DSM
3h 47m$87–390Drive 378.7 mi
cheapest- Drive from Appleton to Des Moinescar 378.7 mi
7h 7m$70–100Bus
- Take the bus from Oshkosh to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Des Moinesbus
13h 31m$119–173Taxi to Green Bay, fly
- Take the taxi from Appleton to Green Bay (GRB)taxi
- Fly from Green Bay (GRB) to Des Moines (DSM)plane GRB - DSM
4h 34m$172–490Bus, train
- Take the bus from Oshkosh to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
14h 10m$228–350Bus, train via Saint Paul
- Take the bus from Oshkosh to Milwaukeebus
- Take the train from Milwaukee to St. Paul-Minneapolistrain
- Take the bus from Saint Paul Union Depot to Des Moinesbus
14h 32m$278–425
Appleton International Airport (ATW) to Des Moines (DSM) flights
Comparing Your Travel Options
The cheapest way to get from Appleton to Des Moines is to drive which costs $65 - $100 and takes 7h 7m.
The fastest way to get from Appleton to Des Moines is to fly which takes 3h 47m and costs $85 - $390.
No, there is no direct bus from Appleton to Des Moines. However, there are services departing from Prospect and Walnut and arriving at Des Moines via Oshkosh, Milwaukee Intermodal Station and Chicago Bus Station. The journey, including transfers, takes approximately 13h 31m.
The distance between Appleton and Des Moines is 334 miles. The road distance is 380.9 miles.
The best way to get from Appleton to Des Moines without a car is to bus which takes 13h 31m and costs $110 - $180.
It takes approximately 3h 47m to get from Appleton to Des Moines, including transfers.
Appleton to Des Moines bus services, operated by Lamers Bus Lines, depart from Oshkosh station.
The best way to get from Appleton to Des Moines is to fly which takes 3h 47m and costs $85 - $390. Alternatively, you can bus, which costs $110 - $180 and takes 13h 31m.
Appleton to Des Moines bus services, operated by Lamers Bus Lines, arrive at Milwaukee station.
Yes, the driving distance between Appleton to Des Moines is 381 miles. It takes approximately 7h 7m to drive from Appleton to Des Moines.
What companies run services between Appleton, WI, USA and Des Moines, IA, USA?
Delta, United Airlines, and two other airlines fly from Appleton International Airport (ATW) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Prospect and Walnut to Des Moines via Church @ Doty - Neenah Transit Center, Oshkosh, Milwaukee, Milwaukee Intermodal Station, and Chicago Bus Station in around 13h 31m.
- Website
- united.com
Flights from Appleton International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $55–350
Flights from Appleton International Airport to Des Moines via Denver
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $120–550
Flights from Green Bay to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $55–350
- Website
- delta.com
Flights from Appleton International Airport to Des Moines via Minneapolis
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $55–350
Flights from Appleton International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $80–420
Flights from Green Bay to Des Moines via Minneapolis
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $60–360
Flights from Green Bay to Des Moines via Detroit
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $80–420
- Website
- aa.com
Flights from Appleton International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 41m
- When
- Every day
- Estimated price
- $55–350
Flights from Green Bay to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $55–350
- Website
- allegiantair.com
Flights from Appleton International Airport to Des Moines via Nashville
- Ave. Duration
- 6h 28m
- When
- Friday
- Estimated price
- $95–470
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Milwaukee to St. Paul-Minneapolis
- Ave. Duration
- 5h 52m
- Frequency
- 3 times a day
- Estimated price
- $170–280
- Website
- Amtrak
- Phone
- 920 496 3600
- Website
- example.com
Bus from Oshkosh to Milwaukee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
Bus from Oshkosh to Milwaukee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
Bus from Oshkosh to Milwaukee
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $14–23
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–85
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Saint Paul Union Depot to Des Moines
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
- Ave. Duration
- 41 min
- Estimated price
- $95–120
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
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There are 255+ hotels available in Des Moines.