There are 6 ways to get from Pueblo to Des Moines by bus, plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Colorado Springs Airport, fly
best- Take the bus from Pueblo, CO to Colorado Springsbus
- Fly from Colorado Springs Airport (COS) to Des Moines (DSM)plane COS - DSM
7h 10m$133–469Bus to Denver, fly
cheapest- Take the bus from Pueblo Transit to Denver Union Stationbus
- Fly from Denver (DEN) to Des Moines (DSM)plane DEN - DSM
6h 2m$95–402Bus
- Take the bus from Pueblo Transit to Denver Union Stationbus Greyhound US1144 / ...
- Take the bus from Denver Union Station to Des Moinesbus Greyhound US0123S
16h 25m$127–209Drive 734.4 mi
- Drive from Pueblo to Des Moinescar 734.4 mi
12h 34m$134–194Fly from Pueblo Memorial Airport
- Fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM)plane PUB - DSM
4h 25m$136–480Bus via Omaha
- Take the bus from Pueblo to Denverbus
- Take the bus from Denver to Omahabus
- Take the bus from Omaha, NE to Des Moinesbus
17h$204–260
Pueblo to Des Moines by bus
Comparing Your Travel Options
The cheapest way to get from Pueblo to Des Moines is to bus which costs $120 - $210 and takes 16h 25m.
The fastest way to get from Pueblo to Des Moines is to fly which takes 4h 25m and costs $130 - $480.
No, there is no direct bus from Pueblo to Des Moines. However, there are services departing from Pueblo Transit and arriving at Des Moines via Denver Union Station. The journey, including transfers, takes approximately 16h 25m.
The distance between Pueblo and Des Moines is 681 miles. The road distance is 738.7 miles.
The best way to get from Pueblo to Des Moines without a car is to bus which takes 16h 25m and costs $120 - $210.
It takes approximately 7h 10m to get from Pueblo to Des Moines, including transfers.
Pueblo to Des Moines bus services, operated by Greyhound USA, depart from Pueblo Transit station.
The best way to get from Pueblo to Des Moines is to bus which takes 16h 25m and costs $120 - $210. Alternatively, you can fly, which costs $130 - $480 and takes 4h 25m.
Pueblo to Des Moines bus services, operated by Greyhound USA, arrive at Denver Union Station.
Des Moines is 1h ahead of Pueblo. It is currently 12:01 in Pueblo and 13:01 in Des Moines.
What companies run services between Pueblo, CO, USA and Des Moines, IA, USA?
You can take a bus from Pueblo Transit to Des Moines via Denver Union Station in around 16h 25m. Alternatively, Key Lime, Southwest Airlines, and United Airlines fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM) once daily.
- Website
- southwest.com
Flights from Colorado Springs Airport to Des Moines via Denver
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $70–390
Flights from Colorado Springs Airport to Des Moines via Chicago Midway
- Ave. Duration
- 8h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–500
Flights from Denver to Des Moines
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $60–350
Flights from Pueblo Memorial Airport to Des Moines via Denver
- Ave. Duration
- 3h 45m
- When
- Tuesday
- Estimated price
- $70–400
Flights from Pueblo Memorial Airport to Des Moines via Denver, Chicago Midway
- Ave. Duration
- 6h 20m
- When
- Thursday and Friday
- Estimated price
- $110–550
- Website
- united.com
Flights from Colorado Springs Airport to Des Moines via Denver
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $70–390
Flights from Colorado Springs Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $100–500
Flights from Denver to Des Moines
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $60–350
Flights from Pueblo Memorial Airport to Des Moines via Denver
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $70–400
- Website
- aa.com
Flights from Colorado Springs Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $100–500
- Website
- delta.com
Flights from Colorado Springs Airport to Des Moines via Minneapolis
- Ave. Duration
- 7h 14m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $85–450
- Website
- flyfrontier.com
Flights from Denver to Des Moines
- Ave. Duration
- 1h 42m
- When
- Monday and Friday
- Estimated price
- $100–360
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- Omnibus Express
Bus from Pueblo, CO to Colorado Springs
- Ave. Duration
- 50 min
- Frequency
- 4 times a day
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Denver Union Station to Des Moines
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $110–180
- Website
- Greyhound
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- $17–26
- Schedules at
- Flixbus USA
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- $17–26
- Schedules at
- Flixbus USA
- Phone
- +1 866 691 9732
- eplasales@eplalimo.com
- Website
- Limousine Express
Bus from Pueblo to Denver
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
- Phone
- +1-877-779-2999
- tony@expressarrow.com
- Website
- Express Arrow
Bus from Denver to Omaha
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $150–180
- Website
- Express Arrow
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Yes, the driving distance between Pueblo to Des Moines is 739 miles. It takes approximately 12h 34m to drive from Pueblo to Des Moines.
Book your Pueblo to Des Moines bus tickets online with Omio and FlixBus.
There are 255+ hotels available in Des Moines.