Lund Stem Cell Center

'Synthetic brain tissue and disease model engineering' Join Lund Stem Cell Center on Wednesday, September 30th, for our next Stem Cell Talk featuring Principal Investigator Henrik Ahlenius! This event is open to all students and researchers at Lunds universitet. Welcome! More information: https://lnkd.in/e7s6-ZmC

Gunilla Karlsson Hedestam, Professor at Karolinska Institutet's Department of Microbiology, Tumor and Cell Biology will be presenting her exciting work on The hidden genetics of human adaptive immunity. Her talk is on September 23!

Join this online information session to learn more about the doctoral programme in Regenerative Medicine and Advanced Therapy Medicinal Products (ATMPs) RAMP-UP, and the upcoming call for research project proposals - open to researchers at Lunds universitet, @Universiteit Leiden, Hannover Medical School, and the DTU - Technical University of Denmark. Whether your research focuses on biomedical (experimental or clinical) science, engineering and technology innovation, health economics and policy, ethics, law or regulation, or the social sciences — your expertise can play a key role in shaping the future of advanced cell, gene, and tissue-based therapies. Information Webinars: 29 September 2026, 12:00 - 13:00 13 October 2026, 12:00 - 13:00 Meeting link to webinars and more information: https://lnkd.in/ej_84wN2

Apart from being Senior Attending Physician at the Department of Infectious Diseases and Hospital Hygiene, Silvio D Brugger has his own research group. Its main focus is on bacterial interspecies interactions in the human host as a source for microbiota-targeted therapies. In addition, he is also working on projects about infectious disease epidemiology and antimicrobial resistance. Join us to hear him talk about "Microbiota-targeted interventions for prevention of infections" on 17 September at Lund Stem Cell Center!

Congratulations!

Welcome to our Open House at Lund Stem Cell Center, where you will have the opportunity to see the MACSima system in action, explore its capabilities and analytical tools, and discuss how the technology could be applied to your own research. Representatives from Lunds universitet, LBIC, and Miltenyi Biotec will be on hand to demonstrate the platform and answer any questions you may have.

When researchers at Lund Stem Cell Center investigated how the molecule UM171 works, a molecule used to make blood stem cells multiply, they made an unexpected connection. The results provide new insights into how one of the most common malignant brain tumours in children could be treated in the future. The molecule works by exploiting a protein called KBTBD4. This causes an important protein structure in the cell, called CoREST, to break down. "The same structure in the cell is also affected by mutations in the KBTBD4 gene, genetic changes that occur in a subgroup of aggressive brain tumours in children. Although the causes differ, the result is the same — the structure breaks down," says Agathees Subramaniam. The researchers also carried out a large-scale drug screen and found that HDAC inhibitors counteract the effects of KBTBD4 mutations. HDAC inhibitors are a type of drug that affects gene activity in cells. The study is an example of so-called drug repurposing, where an already approved drug is given a new use in another disease area. "The findings provide new knowledge about how these brain tumours arise and point to a possible route towards future treatments" says Rohit Sivaprasad. Read full article: https://lnkd.in/e5SMbsJP #lunduniversity #research #drugrepurposing #lundstemcellcenter 📸: Agatheeswaran Subramaniam, researcher at Lund University. Photo: Åsa Hansdotter.

📆 Planning your conference calendar for autumn 2026?   Immunity by Design: In Vivo Immune Cell Engineering will take place on 22–23 October at Lund University, bringing together the immune engineering community for two days of focused discussion.   The meeting co-organized by Filipe Pereira (Lund University), William Nyberg (Karolinska Institutet), and Alexandra Teleki (Uppsala University)spans immune cell therapies, synthetic immunology, delivery technologies, and translational research, with perspectives from both academia and industry. The aim is to connect scientists across academia, healthcare, and industry who are addressing immune modulation from complementary angles. Join us in Lund, Sweden to rethink how to control immune responses, early registration closes on 15 September 2026: ➡️ https://lnkd.in/gJq338UQ   #ScientificConferences #Immunotherapy #ImmunityByDesign

👏 A milestone for stem cell-based therapies in Parkinson’s disease 👏 A landmark study led from Lunds universitet reports the first clinical results from the STEM-PD trial. The study shows that transplanting stem cell-derived dopamine progenitor cells into the brain is feasible. Eight people with Parkinson’s disease received the transplanted cells, and no serious side effects linked to the cell product were observed during the first year of follow-up 🙏 “The possibility of replacing dopamine neurons that are lost in Parkinson’s disease has been a long-standing goal in the field. The findings represent an important milestone for regenerative medicine approaches in Parkinson’s disease and support continued clinical development of stem cell-based therapies,” says Malin Parmar, Professor at Lund University and lead of the STEM-PD programme. The results build on decades of pioneering research in dopamine cell replacement therapy in Lund and close collaboration between researchers, clinicians, and the participating patients. The clinical trial was carried out through collaboration between scientists and clinicians at Lunds universitet University and University of Cambridge ✨ 📸 Skåne University Hospital, Gunnar Gunnarsson. 🔗 https://lnkd.in/dRQ4gRx4 Skånes universitetssjukhus (Skåne University Hospital) Barker Lab Novo Nordisk Cellular Intelligence MultiPark- Multidisciplinary Neuroresearch Medicinska fakulteten, Lunds universitet #ParkinsonsDisease #StemCells #RegenerativeMedicine #Neuroscience #STEMPD