| Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury H Yan, X Duan, H Pan, N Holguin, MF Rai, A Akk, LE Springer, ... Proceedings of the National Academy of Sciences 113 (41), E6199-E6208, 2016 | 180 | 2016 |
| Activation of Wnt signaling by mechanical loading is impaired in the bone of old mice N Holguin, MD Brodt, MJ Silva Journal of Bone and Mineral Research 31 (12), 2215-2226, 2016 | 179 | 2016 |
| Aging diminishes lamellar and woven bone formation induced by tibial compression in adult C57BL/6 N Holguin, MD Brodt, ME Sanchez, MJ Silva Bone 65, 83-91, 2014 | 164 | 2014 |
| Short applications of very low-magnitude vibrations attenuate expansion of the intervertebral disc during extended bed rest N Holguin, J Muir, C Rubin, S Judex The Spine Journal 9 (6), 470-477, 2009 | 107 | 2009 |
| mTORC2 signaling promotes skeletal growth and bone formation in mice J Chen, N Holguin, Y Shi, MJ Silva, F Long Journal of Bone and Mineral Research 30 (2), 369-378, 2015 | 102 | 2015 |
| Early response of mouse joint tissue to noninvasive knee injury suggests treatment targets P Wu, N Holguin, MJ Silva, M Fu, W Liao, LJ Sandell Arthritis & rheumatology 66 (5), 1256-1265, 2014 | 88 | 2014 |
| Adaptation of tibial structure and strength to axial compression depends on loading history in both C57BL/6 and BALB/c mice N Holguin, MD Brodt, ME Sanchez, AA Kotiya, MJ Silva Calcified tissue international 93 (3), 211-221, 2013 | 75 | 2013 |
| Evaluation of loading parameters for murine axial tibial loading: Stimulating cortical bone formation while reducing loading duration D Sun, MD Brodt, HM Zannit, N Holguin, MJ Silva Journal of Orthopaedic Research® 36 (2), 682-691, 2018 | 72 | 2018 |
| Post-traumatic osteoarthritis in mice following mechanical injury to the synovial joint MF Rai, X Duan, JD Quirk, N Holguin, EJ Schmidt, N Chinzei, MJ Silva, ... Scientific reports 7 (1), 45223, 2017 | 68 | 2017 |
| Brief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner N Holguin, G Uzer, FP Chiang, C Rubin, S Judex Journal of applied physiology, 2011 | 55 | 2011 |
| In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin Signaling N Holguin, MJ Silva Scientific reports 8 (1), 11191, 2018 | 47 | 2018 |
| Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis MJ Silva, N Holguin The FASEB Journal 34 (2), 1970-1982, 2020 | 46 | 2020 |
| The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old mice N Holguin, R Aguilar, RA Harland, BA Bomar, MJ Silva Journal of Applied Physiology 116 (12), 1551-1560, 2014 | 43 | 2014 |
| Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization–an in vivo rat model D Wang, A Lai, J Gansau, AC Seifert, J Munitz, K Zaheer, N Bhadouria, ... The Spine Journal 23 (9), 1375-1388, 2023 | 34 | 2023 |
| Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading X Duan, LJ Sandell, N Chinzei, N Holguin, MJ Silva, A Schiavinato, ... PLoS One 12 (4), e0175682, 2017 | 30 | 2017 |
| Rat intervertebral disc health during hindlimb unloading: brief ambulation with or without vibration N Holguin, S Judex Aviation, space, and environmental medicine 81 (12), 1078-1084, 2010 | 26 | 2010 |
| Low-intensity vibrations partially maintain intervertebral disc mechanics and spinal muscle area during deconditioning N Holguin, JT Martin, DM Elliott, S Judex The Spine Journal 13 (4), 428-436, 2013 | 25 | 2013 |
| Early changes in the knee of healer and non‐healer mice following non‐invasive mechanical injury X Duan, MF Rai, N Holguin, MJ Silva, D Patra, W Liao, LJ Sandell Journal of Orthopaedic Research 35 (3), 524-536, 2017 | 22 | 2017 |
| Suppression of Sost/Sclerostin and Dickkopf‐1 augment intervertebral disc structure in mice T Kroon, N Bhadouria, P Niziolek, D Edwards III, R Choi, EL Clinkenbeard, ... Journal of Bone and Mineral Research 37 (6), 1156-1169, 2020 | 15 | 2020 |
| Raloxifene stimulates estrogen signaling to protect against age-and sex-related intervertebral disc degeneration in mice N Bhadouria, AG Berman, JM Wallace, N Holguin Frontiers in Bioengineering and Biotechnology 10, 924918, 2022 | 12 | 2022 |
