| SurvExpress: an online biomarker validation tool and database for cancer gene expression data using survival analysis R Aguirre-Gamboa, H Gomez-Rueda, E Martínez-Ledesma, ... PloS one 8 (9), e74250, 2013 | 747 | 2013 |
| Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project EA Lopera-Maya, A Kurilshikov, A van der Graaf, S Hu, ... Nature genetics 54 (2), 143-151, 2022 | 462 | 2022 |
| A functional genomics approach to understand variation in cytokine production in humans Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ... Cell 167 (4), 1099-1110. e14, 2016 | 380 | 2016 |
| DNA methylation in childhood asthma: an epigenome-wide meta-analysis CJ Xu, C Söderhäll, M Bustamante, N Baïz, O Gruzieva, U Gehring, ... The lancet Respiratory medicine 6 (5), 379-388, 2018 | 254 | 2018 |
| Differential effects of environmental and genetic factors on T and B cell immune traits R Aguirre-Gamboa, I Joosten, PCM Urbano, RG van der Molen, ... Cell reports 17 (9), 2474-2487, 2016 | 217 | 2016 |
| Sex-specific regulation of inflammation and metabolic syndrome in obesity R Ter Horst, ICL van den Munckhof, K Schraa, R Aguirre-Gamboa, ... Arteriosclerosis, thrombosis, and vascular biology 40 (7), 1787-1800, 2020 | 152 | 2020 |
| Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses OB Bakker, R Aguirre-Gamboa, S Sanna, M Oosting, SP Smeekens, ... Nature immunology 19 (7), 776-786, 2018 | 148 | 2018 |
| Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries Z Zheng, S Liu, J Sidorenko, Y Wang, T Lin, L Yengo, P Turley, A Ani, ... Nature Genetics 56 (5), 767-777, 2024 | 144 | 2024 |
| Host genetic regulation of human gut microbial structural variation DV Zhernakova, D Wang, L Liu, S Andreu-Sánchez, Y Zhang, ... Nature 625 (7996), 813-821, 2024 | 137 | 2024 |
| Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study A van Laarhoven, S Dian, R Aguirre-Gamboa, J Avila-Pacheco, ... The Lancet Infectious Diseases 18 (5), 526-535, 2018 | 109 | 2018 |
| ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation NM Peñaranda-Fajardo, C Meijer, Y Liang, BM Dijkstra, ... Cell death & disease 10 (10), 690, 2019 | 96 | 2019 |
| Understanding human immune function using the resources from the Human Functional Genomics Project MG Netea, LAB Joosten, Y Li, V Kumar, M Oosting, S Smeekens, ... Nature medicine 22 (8), 831-833, 2016 | 82 | 2016 |
| Deconvolution of bulk blood eQTL effects into immune cell subpopulations R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ... BMC bioinformatics 21 (1), 243, 2020 | 71 | 2020 |
| Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease X Chu, M Jaeger, J Beumer, OB Bakker, R Aguirre-Gamboa, M Oosting, ... Genome biology 22 (1), 198, 2021 | 67 | 2021 |
| Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease A Van der Graaf, MM Zorro, A Claringbould, U Võsa, R Aguirre-Gamboa, ... Frontiers in Genetics 11, 562434, 2021 | 55 | 2021 |
| The inter-relationship of platelets with interleukin-1β-mediated inflammation in humans RN Tunjungputri, Y Li, PG de Groot, CA Dinarello, SP Smeekens, ... Thrombosis and haemostasis 118 (12), 2112-2125, 2018 | 54 | 2018 |
| An integrative genomics approach identifies KDM4 as a modulator of trained immunity SJ Moorlag, V Matzaraki, JH van Puffelen, C van der Heijden, S Keating, ... European journal of immunology 52 (3), 431-446, 2022 | 53 | 2022 |
| SurvMicro: assessment of miRNA-based prognostic signatures for cancer clinical outcomes by multivariate survival analysis R Aguirre-Gamboa, V Trevino Bioinformatics 30 (11), 1630-1632, 2014 | 49 | 2014 |
| BCG vaccination alters the epigenetic landscape of progenitor cells in human bone marrow to influence innate immune responses SJ Sun, R Aguirre-Gamboa, LCJ de Bree, J Sanz, A Dumaine, ... Immunity 57 (9), 2095-2107. e8, 2024 | 48 | 2024 |
| Epithelial IFNγ signalling and compartmentalized antigen presentation orchestrate gut immunity A Malik, D Sharma, R Aguirre-Gamboa, S McGrath, S Zabala, C Weber, ... Nature 623 (7989), 1044-1052, 2023 | 48 | 2023 |
Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theVerified email at umcg.nl
