| Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase G Haemmerle, A Lass, R Zimmermann, G Gorkiewicz, C Meyer, J Rozman, ... Science 312 (5774), 734-737, 2006 | 1720 | 2006 |
| Cardioprotection and lifespan extension by the natural polyamine spermidine T Eisenberg, M Abdellatif, S Schroeder, U Primessnig, S Stekovic, T Pendl, ... Nature medicine 22 (12), 1428-1438, 2016 | 1234 | 2016 |
| A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice W Enard, S Gehre, K Hammerschmidt, SM Hölter, T Blass, M Somel, ... Cell 137 (5), 961-971, 2009 | 742 | 2009 |
| A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains MM Simon, S Greenaway, JK White, H Fuchs, V Gailus-Durner, S Wells, ... Genome biology 14 (7), R82, 2013 | 623 | 2013 |
| Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes A Vegiopoulos, K Müller-Decker, D Strzoda, I Schmitt, E Chichelnitskiy, ... Science 328 (5982), 1158-1161, 2010 | 572 | 2010 |
| Rapamycin extends murine lifespan but has limited effects on aging F Neff, D Flores-Dominguez, DP Ryan, M Horsch, S Schröder, T Adler, ... The Journal of clinical investigation 123 (8), 3272-3291, 2013 | 442 | 2013 |
| Prevalence of sexual dimorphism in mammalian phenotypic traits NA Karp, J Mason, AL Beaudet, Y Benjamini, L Bower, RE Braun, ... Nature communications 8 (1), 15475, 2017 | 296 | 2017 |
| Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium TF Meehan, N Conte, DB West, JO Jacobsen, J Mason, J Warren, ... Nature genetics 49 (8), 1231-1238, 2017 | 272 | 2017 |
| Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance EÁ Hernández, S Kahl, A Seelig, P Begovatz, M Irmler, Y Kupriyanova, ... The Journal of clinical investigation 127 (2), 695-708, 2017 | 246 | 2017 |
| Inflammation and mitochondrial fatty acid β-oxidation link obesity to early tumor promotion J Khasawneh, MD Schulz, A Walch, J Rozman, MH De Angelis, ... Proceedings of the National Academy of Sciences 106 (9), 3354-3359, 2009 | 241 | 2009 |
| Chemical hybridization of glucagon and thyroid hormone optimizes therapeutic impact for metabolic disease B Finan, C Clemmensen, Z Zhu, K Stemmer, K Gauthier, L Müller, ... Cell 167 (3), 843-857. e14, 2016 | 212 | 2016 |
| Mouse phenotyping H Fuchs, V Gailus-Durner, T Adler, JA Aguilar-Pimentel, L Becker, ... Methods 53 (2), 120-135, 2011 | 172 | 2011 |
| Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics M Hrabě de Angelis, G Nicholson, M Selloum, JK White, H Morgan, ... Nature genetics 47 (9), 969-978, 2015 | 158 | 2015 |
| Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice R De Gasparo, M Pedotti, L Simonelli, P Nickl, F Muecksch, I Cassaniti, ... Nature 593 (7859), 424-428, 2021 | 156 | 2021 |
| Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice K Xie, DP Ryan, BL Pearson, KS Henzel, F Neff, RO Vidal, M Hennion, ... Proceedings of the National Academy of Sciences 115 (10), E2348-E2357, 2018 | 152 | 2018 |
| Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo GS Hönes, H Rakov, J Logan, XH Liao, E Werbenko, AS Pollard, ... Proceedings of the National Academy of Sciences 114 (52), E11323-E11332, 2017 | 138 | 2017 |
| Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43 C Stribl, A Samara, D Trümbach, R Peis, M Neumann, H Fuchs, ... Journal of Biological Chemistry 289 (15), 10769-10784, 2014 | 132 | 2014 |
| Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice K Xie, F Neff, A Markert, J Rozman, JA Aguilar-Pimentel, OV Amarie, ... Nature communications 8 (1), 155, 2017 | 128 | 2017 |
| Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon D Spieler, M Kaffe, F Knauf, J Bessa, JJ Tena, F Giesert, B Schormair, ... Genome research 24 (4), 592-603, 2014 | 128 | 2014 |
| Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice M Horsch, PH Seeburg, T Adler, JA Aguilar-Pimentel, L Becker, ... Journal of Biological Chemistry 286 (21), 18614-18622, 2011 | 125 | 2011 |