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Hai-Yan He
Hai-Yan He
Principal Investigator
Verified email at imb.cams.cn
Title
Cited by
Cited by
Year
A heme-dependent enzyme forms the nitrogen–nitrogen bond in piperazate
YL Du, HY He, MA Higgins, KS Ryan
Nature chemical biology 13 (8), 836-838, 2017
1542017
Two-Enzyme Pathway Links l-Arginine to Nitric Oxide in N-Nitroso Biosynthesis
HY He, AC Henderson, YL Du, KS Ryan
Journal of the American Chemical Society 141 (9), 4026-4033, 2019
852019
Synthetic and biosynthetic routes to nitrogen–nitrogen bonds
HY He, H Niikura, YL Du, KS Ryan
Chemical Society Reviews, 2022
832022
Cloning and elucidation of the FR901464 gene cluster revealing a complex acyltransferase-less polyketide synthase using glycerate as starter units
F Zhang, HY He, MC Tang, YM Tang, Q Zhou, GL Tang
Journal of the American Chemical Society 133 (8), 2452-2462, 2011
662011
The Biosynthetic Gene Cluster of Pyrazomycin—AC‐Nucleoside Antibiotic with a Rare Pyrazole Moiety
G Zhao, S Yao, KW Rothchild, T Liu, Y Liu, J Lian, HY He, KS Ryan, ...
ChemBioChem 21 (5), 644-649, 2020
632020
Quartromicin biosynthesis: two alternative polyketide chains produced by one polyketide synthase assembly line
HY He, HX Pan, LF Wu, BB Zhang, HB Chai, W Liu, GL Tang
Chemistry & biology 19 (10), 1313-1323, 2012
582012
Ferrocene Redox Controlled Reversible Immobilization of Ruthenium Carbene in Ionic Liquid: A Versatile Catalyst for Ring‐Closing Metathesis
G Liu, H He, J Wang
Advanced Synthesis & Catalysis 351 (10), 1610-1620, 2009
552009
A pyridoxal phosphate–dependent enzyme that oxidizes an unactivated carbon-carbon bond
YL Du, R Singh, LM Alkhalaf, E Kuatsjah, HY He, LD Eltis, KS Ryan
Nature Chemical Biology 12 (3), 194-199, 2016
532016
Biosynthesis of the N–N‐Bond‐Containing Compound l‐Alanosine
M Wang, H Niikura, HY He, P Daniel‐Ivad, KS Ryan
Angewandte Chemie International Edition 59 (10), 3881-3885, 2020
502020
Unconventional origin and hybrid system for construction of pyrrolopyrrole moiety in kosinostatin biosynthesis
HM Ma, Q Zhou, YM Tang, Z Zhang, YS Chen, HY He, HX Pan, MC Tang, ...
Chemistry & biology 20 (6), 796-805, 2013
482013
cis-Double bond formation by thioesterase and transfer by ketosynthase in FR901464 biosynthesis
HY He, MC Tang, F Zhang, GL Tang
Journal of the American Chemical Society 136 (12), 4488-4491, 2014
452014
Characterization of QmnD3/QmnD4 for Double Bond Formation in Quartromicin Biosynthesis
LF Wu, HY He, HX Pan, L Han, R Wang, GL Tang
Organic letters 16 (6), 1578-1581, 2014
322014
Baeyer–Villiger Oxidation of Acyl Carrier Protein-Tethered Thioester to Acyl Carrier Protein-Linked Thiocarbonate Catalyzed by a Monooxygenase Domain in FR901464 Biosynthesis
MC Tang, HY He, F Zhang, GL Tang
ACS Catalysis 3 (3), 444-447, 2013
322013
An Unusual Dehydratase Acting on Glycerate and a Ketoreducatse Stereoselectively Reducing α‐Ketone in Polyketide Starter Unit Biosynthesis
HY He, H Yuan, MC Tang, GL Tang
Angewandte Chemie International Edition 53 (42), 11315-11319, 2014
282014
Glycine-derived nitronates bifurcate to O-methylation or denitrification in bacteria
HY He, KS Ryan
Nature Chemistry 13 (6), 599-606, 2021
192021
Heterologous reconstitution of Toxoflavin biosynthesis reveals key pathway intermediates and a cofactor-independent oxidase
K Song, W Li, Z Zhao, H Li, Y Liu, G Zhao, HY He, YL Du
Organic Letters 25 (16), 2918-2922, 2023
152023
Cyclic natural product oligomers: diversity and (bio) synthesis of macrocycles
S Zhang, S Fan, H He, J Zhu, L Murray, G Liang, S Ran, YZ Zhu, MJ Cryle, ...
Chemical Society Reviews, 2025
122025
An engineered biosynthetic–synthetic platform for production of halogenated indolmycin antibiotics
ER Hoffarth, S Kong, HY He, KS Ryan
Chemical science 12 (25), 8817-8821, 2021
42021
Nitramine Formation via a Cryptic Non‐Ribosomal Peptide Synthetase‐Dependent Strategy in N‐Nitroglycine Biosynthesis
HY He, Y Wang, J Zhang, R Shi, S Zhou, S Chen, R Li, W Huang
Angewandte Chemie International Edition, e202507866, 0
4
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Articles 1–19