| The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice C Mo, L Wang, J Zhang, S Numazawa, H Tang, X Tang, XJ Han, J Li, ... Antioxidants & redox signaling 20 (4), 574-588, 2014 | 481 | 2014 |
| Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress S Numazawa, M Ishikawa, A Yoshida, S Tanaka, T Yoshida American Journal of Physiology-Cell Physiology 285 (2), C334-C342, 2003 | 373 | 2003 |
| Lipopolysaccharide‐induced microglial activation induces learning and memory deficits without neuronal cell deathin rats S Tanaka, M Ide, T Shibutani, H Ohtaki, S Numazawa, S Shioda, ... Journal of neuroscience research 83 (4), 557-566, 2006 | 298 | 2006 |
| Redox regulation of the transcriptional repressor Bach1 M Ishikawa, S Numazawa, T Yoshida Free Radical Biology and Medicine 38 (10), 1344-1352, 2005 | 151 | 2005 |
| Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice S Tanaka, A Ishii, H Ohtaki, S Shioda, T Yoshida, S Numazawa Journal of neuroinflammation 10 (1), 907, 2013 | 144 | 2013 |
| Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages T Ashino, R Yamanaka, M Yamamoto, H Shimokawa, K Sekikawa, ... Molecular Immunology 45 (7), 2106-2115, 2008 | 116 | 2008 |
| The anti-inflammatory activity of Phellinus linteus (Berk. & MA Curt.) is mediated through the PKCδ/Nrf2/ARE signaling to up-regulation of heme oxygenase-1 BC Kim, WK Jeon, HY Hong, KB Jeon, JH Hahn, YM Kim, S Numazawa, ... Journal of Ethnopharmacology 113 (2), 240-247, 2007 | 98 | 2007 |
| Redox-sensitive transcription factor Nrf2 regulates vascular smooth muscle cell migration and neointimal hyperplasia T Ashino, M Yamamoto, T Yoshida, S Numazawa Arteriosclerosis, thrombosis, and vascular biology 33 (4), 760-768, 2013 | 97 | 2013 |
| The expression of heme oxygenase-1 gene responded to oxidative stress produced by phorone, a glutathione depletor, in the rat liver; the relevance to activation of c-jun n … T Oguro, M Hayashi, S Nakajo, S Numazawa, T Yoshida The Journal of pharmacology and experimental therapeutics 287 (2), 773-778, 1998 | 91 | 1998 |
| Nrf2-dependent gene expressions: a molecular toxicological aspect S Numazawa, T Yoshida The Journal of toxicological sciences 29 (2), 81-89, 2004 | 88 | 2004 |
| Distinct PKC isozymes regulate bufalin-induced differentiation and apoptosis in human monocytic cells M Kurosawa, Y Tani, S Nishimura, S Numazawa, T Yoshida American Journal of Physiology-Cell Physiology 280 (3), C459-C464, 2001 | 85 | 2001 |
| ERK signaling mediates the induction of inflammatory cytokines by bufalin in human monocytic cells M Kurosawa, S Numazawa, Y Tani, T Yoshida American Journal of Physiology-Cell Physiology 278 (3), C500-C508, 2000 | 82 | 2000 |
| Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats LW Fan, A Kaizaki, LT Tien, Y Pang, S Tanaka, S Numazawa, AJ Bhatt, ... Neuroscience 240, 27-38, 2013 | 81 | 2013 |
| Involvement of Na+, K+‐ATPase inhibition in K562 cell differentiation induced by bufalin S Numazawa, MA Shinoki, H Ito, T Yoshida, Y Kuroiwa Journal of cellular physiology 160 (1), 113-120, 1994 | 79 | 1994 |
| New recreational drug 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (alpha-PVP) activates central nervous system via dopaminergic neuron A Kaizaki, S Tanaka, S Numazawa The Journal of Toxicological Sciences 39 (1), 1-6, 2014 | 77 | 2014 |
| Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide A Kaizaki, LT Tien, Y Pang, Z Cai, S Tanaka, S Numazawa, AJ Bhatt, ... Journal of neuroinflammation 10 (1), 818, 2013 | 72 | 2013 |
| Nrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injury T Ashino, M Yamamoto, S Numazawa Scientific reports 6 (1), 26291, 2016 | 70 | 2016 |
| A physiological role of AMP-activated protein kinase in phenobarbital-mediated constitutive androstane receptor activation and CYP2B induction S Shindo, S Numazawa, T Yoshida Biochemical Journal 401 (3), 735-741, 2007 | 67 | 2007 |
| Heme oxygenase-1 gene expression by a glutathione depletor, phorone, mediated through AP-1 activation in rats T Oguro, M Hayashi, S Numazawa, K Asakawa, T Yoshida Biochemical and biophysical research communications 221 (2), 259-265, 1996 | 63 | 1996 |
| Detection of bisphenol-A in dental materials by gas chromatography-mass spectrometry A MANABE, S KANEKO, S NUMAZAWA, K ITOH, M INOUE, ... Dental materials journal 19 (1), 75-86, 2000 | 59 | 2000 |
