| A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, ... Cell Death & Differentiation 22 (5), 731-742, 2015 | 312 | 2015 |
| Wallerian degeneration is executed by an NMN-SARM1-dependent late Ca2+ influx but only modestly influenced by mitochondria A Loreto, M Di Stefano, M Gering, L Conforti Cell reports 13 (11), 2539-2552, 2015 | 172 | 2015 |
| Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration A Loreto, CS Hill, VL Hewitt, G Orsomando, C Angeletti, J Gilley, C Lucci, ... Neurobiology of disease 134, 104678, 2020 | 144 | 2020 |
| Advances in applying computer-aided drug design for neurodegenerative diseases MM Salman, Z Al-Obaidi, P Kitchen, A Loreto, RM Bill, R Wade-Martins International journal of molecular sciences 22 (9), 4688, 2021 | 135 | 2021 |
| NMN deamidase delays wallerian degeneration and rescues axonal defects caused by NMNAT2 deficiency in vivo M Di Stefano, A Loreto, G Orsomando, V Mori, F Zamporlini, RP Hulse, ... Current Biology 27 (6), 784-794, 2017 | 123 | 2017 |
| Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss MA White, Z Lin, E Kim, CM Henstridge, E Pena Altamira, CK Hunt, ... Acta neuropathologica communications 7 (1), 166, 2019 | 99 | 2019 |
| Independent prognostic value of tumour diameter and tumour necrosis in upper urinary tract urothelial carcinoma G Simone, R Papalia, A Loreto, C Leonardo, S Sentinelli, M Gallucci BJU international 103 (8), 1052-1057, 2009 | 99 | 2009 |
| Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity PD Mabbitt, A Loreto, MA Déry, AJ Fletcher, M Stanley, KC Pao, NT Wood, ... Nature chemical biology 16 (11), 1227-1236, 2020 | 90 | 2020 |
| SARM1 is a multi-functional NAD (P) ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites C Angeletti, A Amici, J Gilley, A Loreto, AG Trapanotto, C Antoniou, ... Iscience 25 (2), 2022 | 85 | 2022 |
| Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain HC Feldman, E Merlini, C Guijas, KE DeMeester, E Njomen, EM Kozina, ... Proceedings of the National Academy of Sciences 119 (35), e2208457119, 2022 | 68 | 2022 |
| Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ... Elife 10, e72823, 2021 | 64 | 2021 |
| Mitochondrial dysfunction as a trigger of programmed axon death E Merlini, MP Coleman, A Loreto Trends in Neurosciences 45 (1), 53-63, 2022 | 62 | 2022 |
| Relationship among symptom score, prostate volume, and urinary flow rates in 543 patients with and without benign prostatic hyperplasia A Sciarra, G D'Eramo, P Casale, A Loreto, M Buscarini, S Di Nicola, ... The Prostate 34 (2), 121-128, 1998 | 54 | 1998 |
| Novel HDAC6 inhibitors increase tubulin acetylation and rescue axonal transport of mitochondria in a model of Charcot–Marie–Tooth type 2F R Adalbert, A Kaieda, C Antoniou, A Loreto, X Yang, J Gilley, T Hoshino, ... ACS chemical neuroscience 11 (3), 258-267, 2019 | 44 | 2019 |
| NMN: The NAD precursor at the intersection between axon degeneration and anti-ageing therapies A Loreto, C Antoniou, E Merlini, J Gilley, MP Coleman Neuroscience Research 197, 18-24, 2023 | 35 | 2023 |
| Relationship among age, prostate‐specific antigen, and prostate volume in men with lower urinary tract symptoms (LUTS) and in different groups of men with and without benign … F Di Silverio, A Sciarra, G D'Eramo, P Casale, A Loreto, F Seccareccia The Prostate 36 (1), 1-7, 1998 | 35 | 1998 |
| The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila AL Rosell, M Paglione, J Gilley, M Kocia, G Perillo, M Gasparrini, ... Elife 11, e80245, 2022 | 29 | 2022 |
| NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy F Rossi, PC Geiszler, W Meng, MR Barron, M Prior, A Herd-Smith, ... Behavioural brain research 339, 140-152, 2018 | 29 | 2018 |
| Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes G Di Pasquale, I Dicembrini, L Raimondi, C Pagano, JM Egan, A Cozzi, ... PLoS One 7 (7), e40074, 2012 | 28 | 2012 |
| NMNAT2 is a druggable target to drive neuronal NAD production JR Tribble, M Jöe, C Varricchio, A Otmani, A Canovai, B Habchi, ... nature communications 15 (1), 6256, 2024 | 24 | 2024 |
