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Michael C. Young
Michael C. Young
Children's Hospital of Philadelphia
Verified email at chop.edu
Title
Cited by
Cited by
Year
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes
Y Sun, MC Young, CH Woodward, JN Danon, HV Truong, S Gupta, ...
Proceedings of the National Academy of Sciences 120 (25), e2304055120, 2023
302023
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes
Y Sun, GF Papadaki, CA Devlin, JN Danon, MC Young, TJ Winters, ...
Science Advances 9 (8), eade7151, 2023
202023
Targeting peptide antigens using a multiallelic MHC I-binding system
H Du, L Mallik, D Hwang, Y Sun, C Kaku, D Hoces, SM Sun, ...
Nature Biotechnology 43 (10), 1683-1693, 2025
172025
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
Y Sun, TJ Florio, S Gupta, MC Young, QF Marshall, SE Garfinkle, ...
Science immunology 8 (90), eadj5792, 2023
172023
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition
AC McShan, D Flores-Solis, Y Sun, SE Garfinkle, JS Toor, MC Young, ...
Nature Communications 14 (1), 8204, 2023
112023
Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules
GF Papadaki, O Ani, TJ Florio, MC Young, JN Danon, Y Sun, D Dersh, ...
Frontiers in Immunology 14, 1116906, 2023
82023
A Chicken Tapasin ortholog can chaperone empty HLA-B∗ 37: 01 molecules independent of other peptide-loading components
GF Papadaki, CH Woodward, MC Young, TJ Winters, GM Burslem, ...
Journal of Biological Chemistry 299 (10), 2023
42023
Regulating IL-2 immune signaling function via a core allosteric structural network
CH Woodward, SO Solieva, D Hwang, VS De Paula, CS Fabilane, ...
Journal of molecular biology 437 (2), 168892, 2025
2025
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Articles 1–8