| Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data T Iwatsubo, N Hirota, T Ooie, H Suzuki, N Shimada, K Chiba, T Ishizaki, ... Pharmacology & therapeutics 73 (2), 147-171, 1997 | 608 | 1997 |
| Evaluation of Ebola virus inhibitors for drug repurposing PB Madrid, RG Panchal, TK Warren, AC Shurtleff, AN Endsley, CE Green, ... ACS infectious diseases 1 (7), 317-326, 2015 | 304 | 2015 |
| A systematic screen of FDA-approved drugs for inhibitors of biological threat agents PB Madrid, S Chopra, ID Manger, L Gilfillan, TR Keepers, AC Shurtleff, ... PloS one 8 (4), e60579, 2013 | 296 | 2013 |
| Computer-aided rational drug design: a novel agent (SR13668) designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling WR Chao, D Yean, K Amin, C Green, L Jong Journal of medicinal chemistry 50 (15), 3412-3415, 2007 | 174 | 2007 |
| Lipopolysaccharide binding protein expression in primary human hepatocytes and HepG2 hepatoma cells. BJ Grube, CG Cochane, RD Ye, CE Green, ME McPhail, RJ Ulevitch, ... Journal of Biological Chemistry 269 (11), 8477-8482, 1994 | 170 | 1994 |
| Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases Z Radić, RK Sit, Z Kovarik, S Berend, E Garcia, L Zhang, G Amitai, ... Journal of Biological Chemistry 287 (15), 11798-11809, 2012 | 152 | 2012 |
| A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3, 5-dimethyl-2-(3-pyridyl … K Nunoya, T Yokoi, K Kimura, K Inoue, T Kodama, M Funayama, ... Pharmacogenetics 8 (3), 239-249, 1998 | 148 | 1998 |
| (R,S)-Ketamine Metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine Increase the Mammalian Target of Rapamycin Function RK Paul, NS Singh, M Khadeer, R Moaddel, M Sanghvi, CE Green, ... Anesthesiology 121 (1), 149-159, 2014 | 145 | 2014 |
| A parallel chiral–achiral liquid chromatographic method for the determination of the stereoisomers of ketamine and ketamine metabolites in the plasma and urine of patients with … R Moaddel, SLV Venkata, MJ Tanga, JE Bupp, CE Green, L Iyer, ... Talanta 82 (5), 1892-1904, 2010 | 127 | 2010 |
| Biliary excretion mechanism of CPT-11 and its metabolites in humans: involvement of primary active transporters XY Chu, Y Kato, K Ueda, H Suzuki, K Niinuma, CA Tyson, V Weizer, ... Cancer research 58 (22), 5137-5143, 1998 | 125 | 1998 |
| Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4 S Kanamitsu, K Ito, CE Green, CA Tyson, N Shimada, Y Sugiyama Pharmaceutical research 17 (4), 419-426, 2000 | 122 | 2000 |
| In Vitro/in Vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans N Hirota, K Ito, T Iwatsubo, CE Green, CA Tyson, N Shimada, H Suzuki, ... Biopharmaceutics & drug disposition 22 (2), 53-71, 2001 | 106 | 2001 |
| Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes Z Radić, T Dale, Z Kovarik, S Berend, E Garcia, L Zhang, G Amitai, ... Biochemical Journal 450 (1), 231-242, 2013 | 105 | 2013 |
| Prediction of in vivo drug-drug interactions between tolbutamide and various sulfonamides in humans based on in vitro experiments K Komatsu, K Ito, Y Nakajima, S Kanamitsu, S Imaoka, Y Funae, ... Drug Metabolism and Disposition 28 (4), 475-481, 2000 | 104 | 2000 |
| Glucuronidation of trans‐resveratrol by human liver and intestinal microsomes and UGT isoforms SS Brill, AM Furimsky, MN Ho, MJ Furniss, Y Li, AG Green, CE Green, ... Journal of pharmacy and pharmacology 58 (4), 469-479, 2006 | 103 | 2006 |
| Variation of hepatic methotrexate 7‐hydroxylase activity in animals and humans S Kitamura, K Sugihara, K Nakatani, S Ohta, T Oh‐Hara, SI Ninomiya, ... IUBMB life 48 (6), 607-611, 1999 | 92 | 1999 |
| Primary active transport of organic anions on bile canalicular membrane in humans K Niinuma, Y Kato, H Suzuki, CA Tyson, V Weizer, JE Dabbs, R Froehlich, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 276 (5 …, 1999 | 87 | 1999 |
| Comparison of amphetamine metabolism using isolated hepatocytes from five species including human. CE Green, SE LeValley, CA Tyson Journal of Pharmacology and Experimental Therapeutics 237 (3), 931-936, 1986 | 86 | 1986 |
| Cytotoxicity measures: choices and methods CA Tyson, CE Green The isolated hepatocyte: use in toxicology and xenobiotic biotransformations …, 1987 | 84 | 1987 |
| Metabolism, cytotoxicity, and genotoxicity of the pyrrolizidine alkaloid senecionine in primary cultures of rat hepatocytes CE Green, HJ Segall, JL Byard Toxicology and Applied Pharmacology 60 (2), 176-185, 1981 | 82 | 1981 |
