| Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties S Schwitalla, AA Fingerle, P Cammareri, T Nebelsiek, SI Göktuna, ... Cell 152 (1), 25-38, 2013 | 1300 | 2013 |
| IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis M Rokavec, MG Öner, H Li, R Jackstadt, L Jiang, D Lodygin, M Kaller, ... The Journal of clinical investigation 124 (4), 1853-1867, 2014 | 867 | 2014 |
| High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity MD Schulz, Ç Atay, J Heringer, FK Romrig, S Schwitalla, B Aydin, ... Nature 514 (7523), 508-512, 2014 | 542 | 2014 |
| Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically TL Putoczki, S Thiem, A Loving, RA Busuttil, NJ Wilson, PK Ziegler, ... Cancer cell 24 (2), 257-271, 2013 | 488 | 2013 |
| Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors S Schwitalla, PK Ziegler, D Horst, V Becker, I Kerle, Y Begus-Nahrmann, ... Cancer cell 23 (1), 93-106, 2013 | 349 | 2013 |
| Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer AM Nicolas, M Pesic, E Engel, PK Ziegler, M Diefenhardt, KB Kennel, ... Cancer cell 40 (2), 168-184. e13, 2022 | 290 | 2022 |
| IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis CK Pallangyo, PK Ziegler, FR Greten Journal of experimental medicine 212 (13), 2253-2266, 2015 | 168 | 2015 |
| Mitophagy in intestinal epithelial cells triggers adaptive immunity during tumorigenesis PK Ziegler, J Bollrath, CK Pallangyo, T Matsutani, Ö Canli, T De Oliveira, ... Cell 174 (1), 88-101. e16, 2018 | 145 | 2018 |
| Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy D Denk, V Petrocelli, C Conche, M Drachsler, PK Ziegler, A Braun, ... Immunity 55 (11), 2059-2073. e8, 2022 | 125 | 2022 |
| AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer J Varga, A Nicolas, V Petrocelli, M Pesic, A Mahmoud, BE Michels, ... Journal of Experimental Medicine 217 (10), e20191515, 2020 | 88 | 2020 |
| Colorectal cancer organoid–stroma biobank allows subtype-specific assessment of individualized therapy responses HF Farin, MH Mosa, B Ndreshkjana, BM Grebbin, B Ritter, C Menche, ... Cancer Discovery 13 (10), 2192-2211, 2023 | 86 | 2023 |
| Complete pathological response after neoadjuvant short-course immunotherapy with ipilimumab and nivolumab in locally advanced MSI-H/dMMR rectal cancer J Trojan, S Stintzing, O Haase, C Koch, P Ziegler, M Demes, I Jelas The oncologist 26 (12), e2110-e2114, 2021 | 55 | 2021 |
| TNF-α–dependent loss of IKKβ-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis AK Mankan, O Canli, S Schwitalla, P Ziegler, J Tschopp, T Korn, ... Proceedings of the National Academy of Sciences 108 (16), 6567-6572, 2011 | 38 | 2011 |
| Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target P Malkomes, I Lunger, E Oppermann, J Lorenz, SF Faqar-Uz-Zaman, ... Cancer Gene Therapy 30 (10), 1346-1354, 2023 | 18 | 2023 |
| Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis T De Oliveira, M Ramakrishnan, MA Diamanti, PK Ziegler, F Brombacher, ... Oncogene 38 (11), 1787-1801, 2019 | 18 | 2019 |
| Evaluation of prognostic factors after primary chemoradiotherapy of anal cancer: a multicenter study of the German Cancer Consortium-Radiation Oncology Group (DKTK-ROG) D Martin, T Schreckenbach, P Ziegler, N Filmann, G Kalinauskaite, ... Radiotherapy and Oncology 167, 233-238, 2022 | 16 | 2022 |
| Fluorescence confocal microscopy on liver specimens for full digitization of transplant pathology MN Kinzler, F Schulze, A Reitz, S Gretser, P Ziegler, O Shmorhun, ... Liver Transplantation 29 (9), 940-951, 2023 | 11 | 2023 |
| How to learn with intentional mistakes: NoisyEnsembles to overcome poor tissue quality for deep learning in computational pathology RS Mayer, S Gretser, LE Heckmann, PK Ziegler, B Walter, H Reis, ... Frontiers in Medicine 9, 959068, 2022 | 11 | 2022 |
| Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer V Marteau, N Nemati, K Handler, D Raju, A Kirchmair, D Rieder, EK Soto, ... Cancer Cell 44 (1), 146-165. e14, 2026 | 7 | 2026 |
| Erk inhibition as a promising therapeutic strategy for high IL-8-secreting and low SPTAN1-expressing colorectal cancer C Meier, G La Rocca, V Nawrot, B Fißlthaler, SJ Overby, K Hourfar, ... International journal of molecular sciences 25 (11), 5658, 2024 | 6 | 2024 |
Julia Slotta-HuspeninaTechnical University of MUNICH, Pathologie StarnbergVerified email at tum.de
