| Fructose and sugar: A major mediator of non-alcoholic fatty liver disease T Jensen, MF Abdelmalek, S Sullivan, KJ Nadeau, M Green, C Roncal, ... Journal of hepatology 68 (5), 1063-1075, 2018 | 1180 | 2018 |
| Phosphoinositide 3-kinase regulates glycolysis through mobilization of aldolase from the actin cytoskeleton H Hu, A Juvekar, CA Lyssiotis, EC Lien, JG Albeck, D Oh, G Varma, ... Cell 164 (3), 433-446, 2016 | 436 | 2016 |
| Intraneuronal Aβ42 accumulation in Down syndrome brain C Mori, ET Spooner, KE Wisniewski, TM Wisniewski, H Yamaguchi, ... Amyloid 9 (2), 88-102, 2002 | 367 | 2002 |
| Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease MB Podlisny, DR Tolan, DJ Selkoe The American journal of pathology 138 (6), 1423, 1991 | 291 | 1991 |
| Climate change and the kidney RJ Johnson, LG Sánchez-Lozada, LS Newman, MA Lanaspa, HF Diaz, ... Annals of Nutrition and Metabolism 74 (Suppl. 3), 38-44, 2019 | 250 | 2019 |
| Uric acid as a cause of the metabolic syndrome. C King, MA Lanaspa, T Jensen, DR Tolan, LG Sánchez-Lozada, ... Contributions to nephrology 192, 88-102, 2018 | 228 | 2018 |
| The Molecular Nature of the F-actin Binding Activity of Aldolase Revealed with Site-directed Mutants (∗) J Wang, AJ Morris, DR Tolan, L Pagliaro Journal of Biological Chemistry 271 (12), 6861-6865, 1996 | 158 | 1996 |
| Fructose contributes to the Warburg effect for cancer growth T Nakagawa, MA Lanaspa, IS Millan, M Fini, CJ Rivard, ... Cancer & Metabolism 8 (1), 1-12, 2020 | 151 | 2020 |
| The complete nucleotide sequence for rabbit muscle aldolase A messenger RNA. DR Tolan, AB Amsden, SD Putney, MS Urdea, EE Penhoet Journal of Biological Chemistry 259 (2), 1127-1131, 1984 | 141 | 1984 |
| Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice MA Lanaspa, A Andres-Hernando, DJ Orlicky, C Cicerchi, C Jang, N Li, ... The Journal of clinical investigation 128 (6), 2226-2238, 2018 | 134 | 2018 |
| Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase KG Hicks, AA Cluntun, HL Schubert, SR Hackett, JA Berg, PG Leonard, ... Science 379 (6636), 996-1003, 2023 | 132 | 2023 |
| Fructose metabolism as a common evolutionary pathway of survival associated with climate change, food shortage and droughts RJ Johnson, P Stenvinkel, P Andrews, LG Sánchez‐Lozada, T Nakagawa, ... Journal of Internal Medicine 287 (3), 252-262, 2020 | 127 | 2020 |
| Molecular analysis of aldolase B genes in hereditary fructose intolerance NCP Cross, TM Cox, R De Franchis, G Sebastio, C Dazzo, DR Tolan, ... The Lancet 335 (8685), 306-309, 1990 | 122 | 1990 |
| Complete amino acid sequence for human aldolase B derived from cDNA and genomic clones. WH Rottmann, DR Tolan, EE Penhoet Proceedings of the National Academy of Sciences 81 (9), 2738-2742, 1984 | 118 | 1984 |
| Targeting of several glycolytic enzymes using RNA interference reveals aldolase affects cancer cell proliferation through a non-glycolytic mechanism CR Lew, DR Tolan Journal of Biological Chemistry 287 (51), 42554-42563, 2012 | 116 | 2012 |
| Hyperuricemia in kidney disease: a major risk factor for cardiovascular events, vascular calcification, and renal damage AA Ejaz, T Nakagawa, M Kanbay, M Kuwabara, A Kumar, FEG Arroyo, ... Seminars in Nephrology 40 (6), 574-585, 2020 | 112 | 2020 |
| Site-directed mutagenesis identifies aspartate 33 as a previously unidentified critical residue in the catalytic mechanism of rabbit aldolase A. AJ Morris, DR Tolan Journal of Biological Chemistry 268 (2), 1095-1100, 1993 | 109 | 1993 |
| Fructose production and metabolism in the kidney T Nakagawa, RJ Johnson, A Andres-Hernando, C Roncal-Jimenez, ... Journal of the American Society of Nephrology 31 (5), 898-906, 2020 | 108 | 2020 |
| Snapshots of Catalysis: the Structure of Fructose-1,6-(bis)phosphate Aldolase Covalently Bound to the Substrate Dihydroxyacetone Phosphate, KH Choi, J Shi, CE Hopkins, DR Tolan, KN Allen Biochemistry 40 (46), 13868-13875, 2001 | 108 | 2001 |
| Lysine-146 of rabbit muscle aldolase is essential for cleavage and condensation of the C3-C4 bond of fructose 1, 6-bis (phosphate) AJ Morris, DR Tolan Biochemistry 33 (40), 12291-12297, 1994 | 107 | 1994 |
Richard J JohnsonUniv of WA, Baylor, Univ of Florida, Univ of COVerified email at ucdenver.edu
