| Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ... Nature 586 (7827), 113-119, 2020 | 844 | 2020 |
| SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling L Miorin, T Kehrer, MT Sanchez-Aparicio, K Zhang, P Cohen, RS Patel, ... Proceedings of the National Academy of Sciences 117 (45), 28344-28354, 2020 | 611 | 2020 |
| MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune, Y Yamamoto, K Sakai, ... Cell reports 34 (2), 2021 | 450 | 2021 |
| Functional landscape of SARS-CoV-2 cellular restriction L Martin-Sancho, MK Lewinski, L Pache, CA Stoneham, X Yin, ME Becker, ... Molecular cell 81 (12), 2656-2668. e8, 2021 | 238 | 2021 |
| A large-scale drug repositioning survey for SARS-CoV-2 antivirals L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, ... BioRxiv, 2020.04. 16.044016, 2020 | 94 | 2020 |
| SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir P Mesci, JS de Souza, L Martin-Sancho, A Macia, A Saleh, X Yin, ... PLoS biology 20 (11), e3001845, 2022 | 69 | 2022 |
| Sofosbuvir protects human brain organoids against SARS-CoV-2 P Mesci, A Macia, A Saleh, L Martin-Sancho, X Yin, C Snethlage, ... BioRxiv, 2020 | 66 | 2020 |
| A BioID-derived proximity interactome for SARS-CoV-2 proteins DG May, L Martin-Sancho, V Anschau, S Liu, RJ Chrisopulos, KL Scott, ... Viruses 14 (3), 611, 2022 | 52 | 2022 |
| Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy L Martin-Sancho, S Tripathi, A Rodriguez-Frandsen, L Pache, ... Nature microbiology 6 (10), 1319-1333, 2021 | 47 | 2021 |
| Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets KM Haas, MJ McGregor, M Bouhaddou, BJ Polacco, EY Kim, TT Nguyen, ... Nature communications 14 (1), 6030, 2023 | 43 | 2023 |
| Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets K Cheng, L Martin‐Sancho, LR Pal, Y Pu, L Riva, X Yin, S Sinha, NU Nair, ... Molecular systems biology 17 (11), e10260, 2021 | 39 | 2021 |
| RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals M Lesch, M Luckner, M Meyer, F Weege, I Gravenstein, M Raftery, ... PLoS pathogens 15 (3), e1007601, 2019 | 39 | 2019 |
| MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells. Cell Rep 34: 108628 X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune, Y Yamamoto, K Sakai, ... | 29 | 2020 |
| The Compound SBI-0090799 Inhibits Zika Virus Infection by Blocking De Novo Formation of the Membranous Replication Compartment L Riva, S Goellner, SB Biering, CT Huang, AN Rubanov, U Haselmann, ... Journal of Virology 95 (22), 10.1128/jvi. 00996-21, 2021 | 28 | 2021 |
| Sec61 inhibitor apratoxin S4 potently inhibits SARS-CoV-2 and exhibits broad-spectrum antiviral activity MO Pohl, L Martin-Sancho, R Ratnayake, KM White, L Riva, QY Chen, ... ACS Infectious Diseases 8 (7), 1265-1279, 2022 | 23 | 2022 |
| Live imaging of airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread ME Becker, L Martin-Sancho, LM Simons, MD McRaven, SK Chanda, ... Nature communications 15 (1), 9480, 2024 | 22 | 2024 |
| mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1 Y Du, JF Hultquist, Q Zhou, A Olson, Y Tseng, T Zhang, M Hong, K Tang, ... Nature communications 11 (1), 2449, 2020 | 19 | 2020 |
| Long-term culture of distal airway epithelial cells allows differentiation towards alveolar epithelial cells suited for influenza virus studies A Imai-Matsushima, L Martin-Sancho, A Karlas, S Imai, T Zoranovic, ... EBioMedicine 33, 230-241, 2018 | 17 | 2018 |
| Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells A Rodriguez-Frandsen, L Martin-Sancho, AP Gounder, MW Chang, ... Journal of virology 94 (4), 10.1128/jvi. 01410-19, 2020 | 16 | 2020 |
| Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans CV Forst, L Martin-Sancho, S Tripathi, G Wang, LG Dos Anjos Borges, ... Science advances 8 (40), eabm5859, 2022 | 12 | 2022 |
